D'Arrigo A, Lazzari G, Fornari G, Vineis C, Costalaia L, Ajmone F
Tumori. 1985 Jun 30;71(3):305-10. doi: 10.1177/030089168507100315.
The case of a woman presenting the clinical and pathologic phenomena of angioimmunoblastic lymphadenopathy (AILD) with dysproteinemia is reported. The patient developed lesions in the lymph nodes, skin, lungs, liver and spleen, and her response to steroid and cyclophosphamide therapy was poor. At autopsy, microscopic findings in the mediastinal and abdominal lymph nodes were consistent with the diagnosis of Hodgkin's disease. Whereas the development of immunoblastic lymphoma is frequent in AILD, Hodgkin's disease is far less common. It is argued that malignant lymphoma in AILD may be the consequence of chronically depressed lymphocyte functions.
报告了一例患有血管免疫母细胞性淋巴结病（AILD）并伴有异常蛋白血症的女性病例，该患者出现了淋巴结、皮肤、肺、肝和脾的病变，且对类固醇和环磷酰胺治疗反应不佳。尸检时，纵隔和腹部淋巴结的显微镜检查结果符合霍奇金病的诊断。虽然免疫母细胞性淋巴瘤在AILD中很常见，但霍奇金病则要少见得多。有人认为，AILD中的恶性淋巴瘤可能是淋巴细胞功能长期受抑制的结果。
