van de Pol Natasja, Visser Elyke H, van Noord Desirée, van der Woude C Janneke, de Vries Annemarie C, de Jonge Vincent, West Rachel L
Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Gastroenterology and Hepatology, Franciscus Gasthuis and Vlietland, Response Number 40233, 3040 VB, Rotterdam, The Netherlands.
Dig Dis Sci. 2025 Apr 17. doi: 10.1007/s10620-025-09030-x.
Patients with inflammatory bowel disease (IBD) tend to be less physical active, while maintaining an active lifestyle has been associated with enhanced disease control, diminished fatigue, and improved quality of life. This study aimed to evaluate the feasibility and potential impact of an exercise program for patients with IBD.
Patients with IBD participated in a 16-week personalized exercise program based on their individual fitness level. Outcome measures included body composition (BMI, muscle mass and fat percentage), physical fitness (based on the Fundamental Motor Skills), quality of life, fatigue, and disease control. For statistical analyses, a paired t test or Wilcoxon signed rank test was used.
In total 32 patients were included, mean age was 50.1 years (SD 12.3), 37.5% were male, and 50% had Crohn's disease. The program was completed by 75% of patients, and average rating of the program was 8.6 out of 10. The program significantly improved fatigue scores (P = 0.013). Quality of life scores improved by an average of 8 points, and disease control showed no significant difference. Additionally, muscle mass (P = 0.020), fat percentage (P = 0.003), lower body strength and coordination (P = 0.006), flexibility (P = 0.002), and speed and endurance (P < 0.001) improved significantly after the program.
This pilot study showed that a personalized exercise program could be feasible for patients with IBD and has the potential to have a positive effect on quality of life and fatigue. These findings underline the importance of physical activity and can be used as a step toward integrating an exercise program in standard IBD care.
炎症性肠病(IBD)患者往往身体活动较少,而保持积极的生活方式与改善疾病控制、减轻疲劳和提高生活质量有关。本研究旨在评估针对IBD患者的运动计划的可行性和潜在影响。
IBD患者根据其个人健康水平参加了为期16周的个性化运动计划。结果指标包括身体成分(BMI、肌肉量和脂肪百分比)、身体素质(基于基本运动技能)、生活质量、疲劳和疾病控制。对于统计分析,使用配对t检验或Wilcoxon符号秩检验。
共纳入32例患者,平均年龄50.1岁(标准差12.3),37.5%为男性,50%患有克罗恩病。75%的患者完成了该计划,该计划的平均评分为8.6分(满分10分)。该计划显著改善了疲劳评分(P = 0.013)。生活质量评分平均提高了8分,疾病控制方面无显著差异。此外,计划实施后肌肉量(P = 0.020)、脂肪百分比(P = 0.003)、下肢力量和协调性(P = 0.006)、柔韧性(P = 0.002)以及速度和耐力(P < 0.001)均有显著改善。
这项初步研究表明,个性化运动计划对IBD患者可能是可行的,并且有可能对生活质量和疲劳产生积极影响。这些发现强调了身体活动的重要性,并可作为将运动计划纳入IBD标准护理的一步。