Zolotov P A, Kesel'man M L, Vnukov V V
Vopr Med Khim. 1985 May-Jun;31(3):45-8.
Chronic treatment (by means of inhalation) of rats with polyamide substances was accompanied by destabilization of erythrocyte membranes causing penetration of hemoglobin into blood serum. Electrophoresis of blood serum proteins in 7.5% polyacrylamide gel exhibited appearance of additional hemoglobin fractions electrophoretic mobility of which corresponded to the Ist and 4th fractions of erythrocyte hemoglobins. Estimation of hemoglobin composition in blood serum might be used for diagnostics of polyamide intoxication.
用聚酰胺物质对大鼠进行慢性（通过吸入方式）处理时，会伴随红细胞膜的不稳定，导致血红蛋白渗入血清。在7.5%聚丙烯酰胺凝胶中对血清蛋白进行电泳，结果显示出现了额外的血红蛋白组分，其电泳迁移率与红细胞血红蛋白的第1和第4组分相对应。血清中血红蛋白成分的评估可用于聚酰胺中毒的诊断。
