Davidson Lydia, Kitikiti Chikomborero, Blencowe Hannah, Fitzgerald Felicity, Moxon Sarah, Chimhini Gwendoline, Chingono Rudo
MARCH Centre, London School of Hygiene & Tropical Medicine, London, UK
The Health Research Institute, Biomedical Research and Training Institute, Harare, Zimbabwe.
BMJ Open. 2025 Apr 17;15(4):e093967. doi: 10.1136/bmjopen-2024-093967.
Neonatal sepsis is a key contributor to neonatal mortality worldwide, and low- and middle-income countries (LMIC) are disproportionately affected. With antimicrobial resistance challenging effective treatment of neonatal sepsis, it is increasingly urgent to improve infection prevention and control (IPC) in LMIC neonatal units (NNU) and reduce transmission of infections. One pathway to improvement which merits further exploration is the collaboration with families to build an IPC intervention.Families are constantly present on neonatal units, and much of the hands-on care for their newborns is given by them. For IPC to be effective, families must adhere to IPC standards within the NNU, but furthermore, any IPC intervention implemented must be feasible and acceptable for families as well as the hospital staff as this will increase uptake and effectiveness of the intervention. This scoping review aims to provide an overview of parental involvement in infection prevention and control in low- and middle-income setting neonatal units.
This protocol was developed in line with the Joanna Briggs Institute recommendations. Searches will be carried out on six databases (Medline, CINAHL, Global Health, EMBASE, Web of Science and Global Index Medicus), and reference searching will be carried out on included studies. The search will be carried out from 2000 to present (end date 28/02/2024), and included languages will be English, French, Spanish and Portuguese. Screening and data extraction will be performed independently by two reviewers, with a third reviewer to resolve conflicts. Results will be reported by narrative synthesis of each sub-question in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines.
This study will be carried out using already published data exclusively and therefore does not require further ethical approval. Results will be disseminated through peer-reviewed publications and conference presentations and through engagement with peers and relevant stakeholders.
Registered with Open Science Framework - https://osf.io/snc7a/?view_only=8ffc39d837594b4388c7394a838c3a9e.
新生儿败血症是全球新生儿死亡的一个关键因素，低收入和中等收入国家（LMIC）受到的影响尤为严重。随着抗菌药物耐药性对新生儿败血症的有效治疗构成挑战，改善低收入和中等收入国家新生儿病房（NNU）的感染预防与控制（IPC）以及减少感染传播变得越来越紧迫。一个值得进一步探索的改善途径是与家庭合作开展IPC干预措施。家庭始终在新生儿病房陪伴，他们为新生儿提供了大量的实际护理。为使IPC有效，家庭必须在新生儿病房内遵守IPC标准，但此外，实施的任何IPC干预措施都必须对家庭以及医院工作人员可行且可接受，因为这将提高干预措施的接受度和有效性。本综述旨在概述低收入和中等收入环境下新生儿病房中家长在感染预防与控制方面的参与情况。
本方案是根据乔安娜·布里格斯研究所的建议制定的。将在六个数据库（Medline、CINAHL、全球健康、EMBASE、科学引文索引和全球医学索引）上进行检索，并对纳入研究进行参考文献检索。检索时间为2000年至目前（截止日期为2024年2月28日），纳入语言将包括英语、法语、西班牙语和葡萄牙语。筛选和数据提取将由两名评审员独立进行，第三名评审员解决冲突。结果将根据系统评价和Meta分析扩展版的首选报告项目（PRISMA-ScR）指南，通过对每个子问题的叙述性综合报告。
本研究将仅使用已发表的数据进行，因此无需进一步的伦理批准。结果将通过同行评审出版物和会议报告以及与同行和相关利益相关者的交流进行传播。
在开放科学框架注册 - https://osf.io/snc7a/?view_only=8ffc39d837594b4388c7394a838c3a9e 。
