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[风湿性二尖瓣疾病患者左心室局部壁功能障碍的频率、定位及范围]

[Frequency, localization and extent of local wall function disorders of the left ventricle in patients with rheumatic mitral valve diseases].

作者信息

Konz K H, Karsch K R, Schwalm G, Jacksch R, Seipel L

出版信息

Z Kardiol. 1985 Jun;74(6):327-34.

PMID:4024683
Abstract

In 59 patients with rheumatic mitral valve disease, local wall motion was assessed by analysing the diastolic and systolic left ventricular silhouette from biplane angiograms with a quantitative radial axes model using 90 radii in each projection. The left ventricle was dissected into 4 segments in the RAO and 2 segments in the LAO projection and a mean radii shortening for each segment was calculated. 27 patients had pure severe mitral stenosis (MS), 10 patients mitral insufficiency (MI) and 22 patients combined mitral valve disease (MSMI). A mean radii shortening less than 25% was diagnosed as wall motion abnormality. In 78% of all patients wall motion abnormalities could be detected in at least one segment. 32% of patients with MS, 27% of patients with MI and 33% of patients with MSMI had wall motion abnormality of the anteroapical wall. In only 8% of patients with MS and in no patients with MI and MSMI was the posterobasal segment disturbed. The anterobasal and diaphragmal wall motion showed wall motion abnormality in 16% and the septal and the posterolateral area in 17% of all patients. 78% of all patients had at least one diseased segment; motion abnormalities of the anteroapical wall (seg. 2) occurred most often whereas the posterobasal area (seg. 4) was diseased in only 4% of all patients. Ejection fraction was severely impaired (less than 55%) in 7 patients only (5 of these patients had MS) with wall motion abnormalities in more than 4 segments. There was no correlation between the extent of valve disease and occurrence and extent of wall motion abnormalities.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在59例风湿性二尖瓣疾病患者中,通过使用定量径向轴模型分析双平面血管造影舒张期和收缩期左心室轮廓来评估局部室壁运动,每个投影使用90条半径。在右前斜位将左心室分为4段,左前斜位分为2段,并计算每段的平均半径缩短率。27例患者为单纯重度二尖瓣狭窄(MS),10例为二尖瓣关闭不全(MI),22例为二尖瓣联合病变(MSMI)。平均半径缩短率小于25%被诊断为室壁运动异常。在所有患者中,78%至少有一个节段可检测到室壁运动异常。32%的MS患者、27%的MI患者和33%的MSMI患者存在心尖前壁室壁运动异常。仅8%的MS患者、MI和MSMI患者均无后基底段受累。所有患者中,16%的心前基底段和膈面室壁运动显示异常,17%的室间隔和后外侧区域显示异常。78%的患者至少有一个病变节段;心尖前壁(节段2)运动异常最常见,而后基底段(节段4)仅4%的患者受累。仅7例患者(其中5例为MS)的射血分数严重受损(小于55%),这些患者有超过4个节段的室壁运动异常。瓣膜疾病的程度与室壁运动异常的发生和程度之间无相关性。(摘要截短于250字)

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