Iontov A S, Granstrem E E, Shefer V F, Epshteĭn I I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(6):813-8.
An electron microscopy study was conducted on the material of biopsies from the removed epileptic foci localized in the hippocamp and fields 21 and 38 of the temporal cortex of 11 patients with temporal epilepsy. There was the constant presence of so-called dark and altered light neurocytes whose cytoplasm had experienced considerable changes and was saturated with various inclusions. The axons and dendrites of the cells underwent peculiar degeneration. The authors revealed multiple agglutination of synaptic vesicles in the preterminals and synaptic buds, and also dark degeneration of the axonal endings in the absence of Waller's degeneration of axons. Marked changes in the walls of the capillaries were also found.
对11例颞叶癫痫患者切除的位于海马及颞叶皮质21区和38区的癫痫病灶活检材料进行了电子显微镜研究。持续存在所谓的暗神经细胞和变性亮神经细胞,其细胞质经历了相当大的变化,并充满了各种内含物。细胞的轴突和树突发生了特殊的变性。作者发现终末前和突触芽中的突触小泡多处凝集,并且在轴突无华勒变性的情况下轴突终末出现暗变性。还发现毛细血管壁有明显变化。