Wang Haichen, Li Qinglin, Han Shaoqi, Tian Hu
Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Front Oncol. 2025 Apr 3;15:1524974. doi: 10.3389/fonc.2025.1524974. eCollection 2025.
Gallbladder cancer (GBC) accounts for 1.7% of all cancer-related deaths. Neuroendocrine carcinoma of the gallbladder (GB-NEC) is a rare subtype of GBC that is more malignant than GBC. Small-cell neuroendocrine carcinoma of the gallbladder (GB-SCNEC) is a rare malignant tumor with a low incidence. To date, no universally accepted or satisfactory treatment exists. This case report details the clinical presentation, diagnostic process, and treatment strategy of a patient with GB-SCNEC. The analysis of this rare case is intended to provide clinicians with diagnostic and therapeutic insights for future research.
胆囊癌(GBC)占所有癌症相关死亡人数的1.7%。胆囊神经内分泌癌(GB-NEC)是GBC的一种罕见亚型,其恶性程度高于GBC。胆囊小细胞神经内分泌癌(GB-SCNEC)是一种发病率低的罕见恶性肿瘤。迄今为止,尚无普遍接受或令人满意的治疗方法。本病例报告详细介绍了一名GB-SCNEC患者的临床表现、诊断过程和治疗策略。对这一罕见病例的分析旨在为临床医生提供未来研究的诊断和治疗思路。