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使用腹壁下深动脉穿支(DIEP)皮瓣进行乳房切除术后乳房重建:一项四年研究的临床和法医学见解

Breast Reconstruction After Mastectomy Using a Deep Inferior Epigastric Perforator (DIEP) Flap: Clinical and Medico-Legal Insights From a Four-Year Study.

作者信息

Savva Demetris, Nittari Giulio, Gibelli Filippo, Ricci Giovanna, Dalitis Savvas, Fotiou Antonia, Michael Phanos

机构信息

Department of Plastic Reconstructive and Aesthetic Surgery Nicosia General Hospital Nicosia Cyprus.

School of Pharmaceutical Sciences and Health Products University of Camerino Camerino Italy.

出版信息

Health Sci Rep. 2025 Apr 16;8(4):e70499. doi: 10.1002/hsr2.70499. eCollection 2025 Apr.

DOI:10.1002/hsr2.70499
PMID:40248398
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12003920/
Abstract

AIMS

Breast reconstruction after mastectomy is nowadays a gold standard in therapy of breast cancer patients. Free deep inferior epigastric perforator (DIEP) flap reconstruction is a favorable method when traditional implants fail or are not viable, especially after radiotherapy. The aim of this paper is to present the results of a case series study of 40 patients operated on with DIEP flap from January 2020 to October 2023, in Plastic, Reconstructive and Aesthetic Surgery Department in Nicosia General Hospital, Cyprus, complications and wound management, reoperation rates, as well as to examine these results from a medico-legal perspective, to highlight the most significant medico-legal implications of this demanding, surgical procedure.

METHOD

Forty patients were included in this study with unilateral or bilateral free DIEP reconstruction, from January 2020 to October 2023, in Plastic, Reconstructive and Aesthetic Surgery Department in Nicosia General Hospital, Cyprus. Demographics, preoperative conditions, hospitalization days, complication rates, and reoperation rates were analyzed as well as satisfaction rates of patients were evaluated.

RESULTS

This original article highlighted a number of issues of strict medico-legal interest, including the importance of informed consent in the case of demanding procedures for reconstructive and esthetic purposes, the assessment of standards of care in the evaluation of medical liability, and the existence of an obligation of means or results on the reconstructive surgeon's part.

CONCLUSIONS

DIEP breast reconstruction after mastectomy is a challenging but safe and with well postoperative results operation that should be employed in cases traditional implant reconstruction fail or not feasible due to other parameters. Innovative and demanding reconstructive, esthetic surgery procedures are characterized by particularly significant aspects of medico-legal interest, which deserve careful consideration by both the scientific community and patients involved.

摘要

目的

乳房切除术后乳房重建如今是乳腺癌患者治疗的金标准。当传统植入物失败或不可行时,尤其是在放疗后,游离腹壁下深动脉穿支(DIEP)皮瓣重建是一种理想的方法。本文的目的是展示2020年1月至2023年10月在塞浦路斯尼科西亚综合医院整形、重建与美容外科接受DIEP皮瓣手术的40例患者的病例系列研究结果、并发症及伤口处理、再次手术率,并从法医学角度审视这些结果,以突出这一要求苛刻的外科手术最重要的法医学影响。

方法

本研究纳入了2020年1月至2023年10月在塞浦路斯尼科西亚综合医院整形、重建与美容外科接受单侧或双侧游离DIEP重建的40例患者。分析了人口统计学、术前状况、住院天数、并发症发生率和再次手术率,并评估了患者的满意度。

结果

这篇原创文章突出了一些具有严格法医学意义的问题,包括在进行重建和美容目的的苛刻手术时知情同意的重要性、评估医疗责任时的护理标准、以及重建外科医生方面手段或结果义务的存在。

结论

乳房切除术后DIEP乳房重建是一项具有挑战性但安全且术后效果良好的手术,在传统植入物重建失败或因其他因素不可行的情况下应采用。创新且要求苛刻的重建、美容外科手术具有特别重要的法医学意义,值得科学界和相关患者仔细考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff4/12003920/08ba3e7ef7c3/HSR2-8-e70499-g008.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff4/12003920/1ad949a1bde3/HSR2-8-e70499-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ff4/12003920/08ba3e7ef7c3/HSR2-8-e70499-g008.jpg

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本文引用的文献

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Current status of autologous breast reconstruction in Europe: how to reduce donor site morbidity.欧洲自体乳房重建的现状:如何降低供区并发症发生率
Gland Surg. 2023 Dec 26;12(12):1760-1773. doi: 10.21037/gs-23-288. Epub 2023 Dec 22.
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Breast reconstruction with latissimus dorsi flap: a comprehensive review and case series.背阔肌肌皮瓣乳房重建:综述与病例系列
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Are Surgical Drains Needed in DIEP Flap Surgery? The Drain-Free DIEP Flap Concept.
是否需要在 DIEP 皮瓣手术中使用引流管?无引流管 DIEP 皮瓣概念。
Plast Reconstr Surg. 2023 Oct 1;152(4):708-714. doi: 10.1097/PRS.0000000000010340. Epub 2023 Mar 3.
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Teaching Microsurgical Breast Reconstruction-A Retrospective Cohort Study.显微外科乳房重建教学——一项回顾性队列研究
J Clin Med. 2021 Dec 14;10(24):5875. doi: 10.3390/jcm10245875.
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Microsurgical Tissue Transfer in Breast Reconstruction.乳房重建中的显微外科组织移植
Clin Plast Surg. 2017 Apr;44(2):345-359. doi: 10.1016/j.cps.2016.12.002. Epub 2017 Feb 13.
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The DIEP flap breast reconstruction: Starting from scratch in a university hospital.腹壁下动脉穿支皮瓣乳房重建术:一所大学医院的从零开始之路。
Ann Chir Plast Esthet. 2015 Jun;60(3):171-8. doi: 10.1016/j.anplas.2015.02.005. Epub 2015 Mar 21.
7
Current evidence for postoperative monitoring of microvascular free flaps: a systematic review.微血管游离皮瓣术后监测的当前证据:一项系统评价。
Ann Plast Surg. 2015 May;74(5):621-32. doi: 10.1097/SAP.0b013e3181f8cb32.
8
Advancements in free flap monitoring in the last decade: a critical review.过去十年中游离皮瓣监测的进展:一项批判性综述。
Plast Reconstr Surg. 2010 Aug;126(2):679. doi: 10.1097/PRS.0b013e3181df720b.
9
Breast Reconstruction with the free TRAM or DIEP flap: patient selection, choice of flap, and outcome.游离腹直肌肌皮瓣或腹壁下动脉穿支皮瓣乳房再造:患者选择、皮瓣选择及效果
Plast Reconstr Surg. 2002 Aug;110(2):466-75; discussion 476-7. doi: 10.1097/00006534-200208000-00015.
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Plast Reconstr Surg. 2000 May;105(6):2266. doi: 10.1097/00006534-200005000-00062.