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毒芹(毒参)急性中毒

Acute Intoxication With Poison Hemlock (Conium maculatum).

作者信息

Nunes João, Pina Sergio, Oliveira Ana Carolina, Moreno Javier, Pérez Pilar

机构信息

Critical Care Medicine, Unidade Local de Saúde (ULS) Algarve - Hospital de Faro, Faro, PRT.

出版信息

Cureus. 2025 Mar 18;17(3):e80763. doi: 10.7759/cureus.80763. eCollection 2025 Mar.

Abstract

Poison hemlock () is regarded as one of the most poisonous plants worldwide, and it can easily be misidentified as edible species as celery, parsnip (for their leaves), or carrots (for their roots). Toxicity comes from piperidine alkaloids, which mimic nicotine effect on the autonomous nervous system giving a clinical picture of nicotinic syndrome with an initial excitatory phase and secondary inhibitory one. In Portugal, this plant is used as an ancient technique for river fishing. Death comes from respiratory arrest and hemodynamic collapse; rapid diagnosis and medical support are essential for successful treatment. We present two cases of different degrees of intoxication with total recovery.

摘要

毒芹被认为是世界上毒性最强的植物之一,它很容易被误认成可食用物种,如芹菜、欧洲防风草(因其叶子)或胡萝卜(因其根部)。其毒性来自哌啶生物碱,这些生物碱会模拟尼古丁对自主神经系统的作用,从而呈现出烟碱综合征的临床表现,初期为兴奋期,继而进入抑制期。在葡萄牙,这种植物被用作一种古老的河钓技术。死亡原因是呼吸骤停和血流动力学崩溃;快速诊断和医疗支持对于成功治疗至关重要。我们介绍两例不同程度中毒但完全康复的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f86d/12005235/df45ada5a53c/cureus-0017-00000080763-i01.jpg

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