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单机构中头下垂综合征保守治疗与手术治疗的疗效:病例系列及文献综述

Outcomes of Conservative Versus Surgical Treatment of Dropped Head Syndrome in a Single Institution: A Case Series and Review of the Literature.

作者信息

Liu Serena B, Wassef Catherine E, Mesfin Addisu, Molinari Robert

机构信息

Orthopedic Surgery, University of Rochester Medical Center, Rochester, USA.

Neurosurgery, University of Rochester Medical Center, Rochester, USA.

出版信息

Cureus. 2025 Mar 18;17(3):e80777. doi: 10.7759/cureus.80777. eCollection 2025 Mar.

Abstract

Dropped head syndrome (DHS), also known as camptocephalia, is characterized by a mobile chin-on-chest deformity from hypotonia of the cervical extensor muscle or hypertonia of the anterior neck muscles. There remains a paucity of quality published literature on this topic, particularly its management. The objective of this study is to identify radiographic and clinical outcomes of surgery as compared to nonsurgical treatment, to summarize the literature, and to create a decision-making paradigm for managing patients with DHS. As such, we report outcomes of our retrospective chart review series as well as a literature review on the etiology, management options, and outcomes. In our series, we examined the radiographic parameters of the C2-C7 Cobb angle, C2-C7 sagittal vertical axis (SVA), and T1 slope, as well as clinically reported outcomes of conservatively managed (CM; N = 8) and surgically managed (SM; N = 5) interventions on 13 patients with DHS at a single institution. At initial presentation, the CM group had poorer C2-C7 Cobb angle (-37.8 ± 3.2 degrees) and C2-C7 SVA (77.1 ± 10.6 mm) in comparison to the SM group (-21.0 ± 30.3 degrees and 56.9 ± 16.2 mm, respectively). We found a statistically significant improvement in the C2-C7 Cobb angle and T1 slope (p-value of 0.024 and 0.019, respectively) after surgery. Clinically, only one patient in the CM group (20%) reported improvement versus six patients in the SM group (80%). Our study is limited by its small sample size, albeit it is the largest cohort of patients treated at a single institution in the United States to our knowledge. Although our cohort was comprised of heterogeneous etiologies and patient comorbidities, we found that surgery can be beneficial in the right patient. To aid in proper surgical selection, we provide an algorithm for workup and management of DHS.

摘要

低头综合征(DHS),也称为头部前倾,其特征是由于颈伸肌肌张力减退或颈部前方肌肉张力亢进导致可活动的下巴抵胸畸形。关于这个主题,尤其是其治疗方法,高质量的已发表文献仍然很少。本研究的目的是确定手术与非手术治疗相比的影像学和临床结果,总结文献,并为管理DHS患者创建一个决策范例。因此,我们报告了回顾性病历审查系列的结果以及关于病因、治疗选择和结果的文献综述。在我们的系列研究中,我们检查了C2-C7 Cobb角、C2-C7矢状垂直轴(SVA)和T1斜率的影像学参数,以及在单一机构对13例DHS患者进行保守治疗(CM;N = 8)和手术治疗(SM;N = 5)干预后的临床报告结果。在初次就诊时,与SM组相比,CM组的C2-C7 Cobb角(-37.8±3.2度)和C2-C7 SVA(77.1±10.6毫米)更差(分别为-21.0±30.3度和56.9±16.2毫米)。我们发现手术后C2-C7 Cobb角和T1斜率有统计学意义的改善(p值分别为0.024和0.019)。临床上,CM组只有1例患者(20%)报告有改善,而SM组有6例患者(80%)报告有改善。我们的研究受到样本量小的限制,尽管据我们所知,这是美国单一机构治疗的最大患者队列。虽然我们的队列包括不同的病因和患者合并症,但我们发现手术对合适的患者可能有益。为了帮助进行正确的手术选择,我们提供了一个DHS检查和管理的算法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0da/12005606/37eb0269baff/cureus-0017-00000080777-i01.jpg

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