Developments in tissue engineering, diagnosis, and therapy of oral diseases can be made possible by nanotechnology. The purpose of this scoping review was to assess the state of nanotechnology applications in oral pathology at the moment. A thorough search for research published between 2000 and 2024 was done using various online data bases. Relevant studies were identified, screened, and included in accordance with the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) guidelines standards as per the selection criterion. A total of 57 studies satisfied the requirements for inclusion. Significant findings show that in oral disease, nanotechnology greatly enhances treatment delivery, regeneration capacity, and diagnostic accuracy. Among the most promising tools identified were nanofibers, liposomes, quantum dots, and gold nanoparticles. In the field of oral pathology, nanotechnology has great potential for novel approaches to early diagnosis, targeted therapy, and tissue regeneration. However, additional investigation are needed to solve safety and biocompatibility challenges.