Cepeda E E, Shankaran S
Acta Paediatr Scand. 1985 Jul;74(4):545-8. doi: 10.1111/j.1651-2227.1985.tb11026.x.
Three bilirubin binding tests (hydroxybenzene-azobenzoic acid dye binding method, the estimation of unbound bilirubin by horseradish peroxidase assay and the saturation of albumin by the salicylate saturation index) were performed on pre-exchange samples of blood and repeated 24 hours after the procedure. No significant improvement in bilirubin binding was found even in infants receiving as many as four exchange transfusions. Based on these bilirubin binding tests, we find no evidence that the criteria for subsequent exchange transfusions should be different from the first exchange transfusion.
对换血前的血样进行了三项胆红素结合试验（羟基苯偶氮苯甲酸染料结合法、用辣根过氧化物酶测定法估算未结合胆红素以及水杨酸饱和指数法测定白蛋白饱和度），并在操作24小时后重复进行。即使是接受多达四次换血的婴儿，也未发现胆红素结合有明显改善。基于这些胆红素结合试验，我们没有发现证据表明后续换血的标准应与首次换血不同。
