Fradet L, Benchekri A, Tisserand R, Cazalets J-R, Amestoy A, Lemonnier E, Cottenceau H, Yentes J M, Bidet-Ildei C
Université de Poitiers, ISAE-ENSMA, CNRS, PPrime, Poitiers, France.
Université de Poitiers, Université de Tours, CNRS, CeRCA, Poitiers, France.
J Autism Dev Disord. 2025 Apr 18. doi: 10.1007/s10803-025-06815-x.
Autistic children (AT) are known to exhibit distinct postural control patterns compared to neurotypical (NT) children. However, identifying and interpreting these differences can be complex due to the wide range of variables used to analyse Centre of Pressure (CoP) trajectories. This study aims to elucidate the specific characteristics of postural control in AT children by identifying the most discriminative CoP variables that distinguish them from NT children. The study evaluated 24 AT and 24 NT children while they stood on a force plate for 30 s under three conditions: eyes open (EO), eyes closed (EC), and the feet on a foam pad with eyes open (EOF). A total of 75 variables-including frequential, linear, and non-linear variables-were extracted from the CoP trajectory. These variables, expressed as the rate of change between the EC and EOF conditions relative to the EO condition, were compared between the AT and NT groups. A best-subsets approach was used to identify the most discriminative variables, and Pearson correlations were calculated to assess their relationship with age and Social Responsiveness Scale (SRS) scores. Of the 75 variables analysed, 15 showed significant differences between the AT and NT groups. The best-subsets analysis and the correlations revealed that variables such as the rate of change between the EOF and EO conditions, and the root mean square of the trembling component of the CoP trajectory, were particularly discriminative. Autistic children demonstrated a more rigid and regular CoP trajectory, particularly in the EO condition, compared to NT children. These findings suggest that AT children have greater difficulty integrating multisensory information and an increased reliance on supraspinal processes for postural control.
与神经正常（NT）儿童相比，自闭症儿童（AT）表现出独特的姿势控制模式。然而，由于用于分析压力中心（CoP）轨迹的变量范围广泛，识别和解释这些差异可能很复杂。本研究旨在通过识别最具区分性的CoP变量来阐明AT儿童姿势控制的具体特征，这些变量将他们与NT儿童区分开来。该研究评估了24名AT儿童和24名NT儿童，他们在三种条件下站在测力板上30秒：睁眼（EO）、闭眼（EC）以及睁眼站在泡沫垫上（EOF）。从CoP轨迹中总共提取了75个变量，包括频率、线性和非线性变量。将这些变量表示为EC和EOF条件相对于EO条件的变化率，并在AT组和NT组之间进行比较。采用最佳子集法来识别最具区分性的变量，并计算皮尔逊相关性以评估它们与年龄和社会反应量表（SRS）分数的关系。在分析的75个变量中，有15个在AT组和NT组之间存在显著差异。最佳子集分析和相关性表明，诸如EOF和EO条件之间的变化率以及CoP轨迹颤抖分量的均方根等变量具有特别的区分性。与NT儿童相比，自闭症儿童表现出更僵硬和规则的CoP轨迹，尤其是在EO条件下。这些发现表明，AT儿童在整合多感官信息方面有更大困难，并且在姿势控制方面对脊髓上的过程依赖增加。
