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家禽感染综述。

Review of Infections of Poultry.

作者信息

Reynolds Donald L, Hille Matthew M, Jia Beibei

机构信息

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0907,

School of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, NE 68583-0907.

出版信息

Avian Dis. 2025 Apr;68(S1):412-420. doi: 10.1637/aviandiseases-D-24-00084.

Abstract

organisms are Gram-positive cocci that are ubiquitous in the environment, occurring in water and soil, and are commensal inhabitants of the intestinal tracts of both vertebrate and invertebrate animals. They are considered opportunists and possess many virulence-encoding traits, including the formation of biofilms and toxins. produces cytolysin, which is a unique toxin having activity against both eukaryotic and prokaryotic cells. Cytolysin causes hemolysis of red blood cells and has also been termed hemolysin. organisms are intrinsically resistant to some antibiotics and can transmit antimicrobial resistance to other microorganisms. In poultry, there is ample evidence to indicate that can be egg transmitted, causing decreased hatchability of eggs. has been found to rapidly spread among hatchlings that are exposed in the hatcher. In older birds, some isolates cause amyloid arthropathy. Various methods have been developed to assess isolates for virulence-encoding traits, including Multilocus sequence typing and embryo lethality assays. However, much variability occurs in interpreting the results of these methods and the correlation between genotypes, phenotypes, and virulence has not been well established. The virulence traits and pathogenesis of in poultry need to be elucidated further.

摘要

该微生物为革兰氏阳性球菌,在环境中普遍存在,见于水和土壤中,也是脊椎动物和无脊椎动物肠道的共生菌。它们被视为机会致病菌,具有许多编码毒力的特性,包括形成生物膜和毒素。该微生物产生细胞溶素,这是一种对真核细胞和原核细胞均有活性的独特毒素。细胞溶素可导致红细胞溶血,也被称为溶血素。该微生物对某些抗生素具有内在抗性,并且能够将抗微生物抗性传递给其他微生物。在家禽中,有充分证据表明该微生物可通过蛋传播,导致蛋的孵化率降低。已发现该微生物在孵化箱中暴露的雏鸡中迅速传播。在成年禽类中,一些该微生物分离株可引起淀粉样关节病。已开发出多种方法来评估该微生物分离株的毒力编码特性,包括多位点序列分型和胚胎致死率测定。然而,在解释这些方法的结果时存在很大差异,并且基因型、表型和毒力之间的相关性尚未完全确立。该微生物在家禽中的毒力特性和发病机制需要进一步阐明。

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