Wade Ben, Rautenschlein Silke, Hao Van T T, Moore Robert J
School of Science, Royal Melbourne Institute of Technology (RMIT) University, Bundoora, Victoria 3083, Australia.
Clinic for Poultry, University of Veterinary Medicine, 30559 Hanover, Germany.
Avian Dis. 2025 Apr;68(S1):481-489. doi: 10.1637/aviandiseases-D-24-00090.
Spotty liver disease is an economically important, emerging disease that primarily impacts the cage-free poultry layer industry. While this disease remains understudied, several important findings have been reported in the last 5 yr that warrant an updated review of the field. These include updated cost estimates of disease, insights into the molecular biology of the causative agent, the identification of a second bacterium responsible for disease production, insights into disease epidemiology and interventions, and the generation of new molecular tools for further study.