Greenhalgh Christy C, Bigham Amy, Shanahan Tonya D
Moffett & Sanders School of Nursing, Samford University, Birmingham, Alabama.
Adv Emerg Nurs J. 2025;47(2):103-107. doi: 10.1097/TME.0000000000000562. Epub 2025 Apr 16.
Diabetic ketoacidosis (DKA), seen with relative frequency in the emergency department, is a potentially life-threatening complication of both type I diabetes mellitus and type II diabetes mellitus (T2DM) characterized by hyperglycemia, ketosis, and acidosis. However, an uncommon variation of DKA, termed euglycemic diabetic ketoacidosis (euDKA) has been increasing in frequency due to the abundance of patients with T2DM being managed on sodium-glucose cotransporter-2 inhibitors, which pose an increased risk of euDKA. The diagnosis of euDKA can be elusive as the typical presentation of substantial hyperglycemia is absent, which can lead to delayed diagnosis and treatment. This case study highlights the clinical presentation and management of euDKA patients to help increase awareness.
糖尿病酮症酸中毒（DKA）在急诊科较为常见，是1型糖尿病和2型糖尿病（T2DM）的一种潜在危及生命的并发症，其特征为高血糖、酮血症和酸中毒。然而，一种不常见的DKA变异类型，即正常血糖性糖尿病酮症酸中毒（euDKA），由于大量使用钠-葡萄糖协同转运蛋白2抑制剂治疗T2DM患者，其发生率一直在上升，而这会增加euDKA的风险。euDKA的诊断可能难以捉摸，因为缺乏典型的显著高血糖表现，这可能导致诊断和治疗延迟。本病例研究强调了euDKA患者的临床表现和管理，以帮助提高认识。
