Anderson Elizabeth J, Love Tracy, Riès Stéphanie K
Joint Doctoral Program in Language and Communicative Disorders, San Diego State University/University of California San Diego, San Diego, CA, USA.
School of Speech, Language, and Hearing Sciences, San Diego State University, San Diego, CA, USA.
Cogn Neuropsychol. 2025 Apr 18:1-16. doi: 10.1080/02643294.2025.2492038.
Speech monitoring abilities vary among individuals with stroke-induced aphasia, with brain lesion location as a potential factor. Left posterior temporal cortex (pLTC) regions are thought to be central to lexical access. We tested whether pLTC lesions affect the medial frontal action monitoring system, as indexed by the Error-Related Negativity (ERN), which has been implicated in inner speech monitoring. Electroencephalography was recorded during picture naming in 11 individuals with pLTC lesions (4 from each of two institutions included in EEG analyses), 7 with lesions sparing the pLTC (6 included), and 20 matched controls (14 included). Individuals with pLTC lesions were slower and less accurate than other groups. Individuals with lesions sparing the pLTC showed the expected ERN; individuals with pLTC lesions did not. Therefore, the medial frontal monitoring mechanism may be compromised when regions central to lexical access are damaged, indicating that pLTC-medial frontal interactions may support inner speech monitoring.
中风引起的失语症患者的言语监测能力因人而异，脑损伤部位可能是一个因素。左后颞叶皮质（pLTC）区域被认为是词汇提取的核心。我们测试了pLTC损伤是否会影响内侧额叶动作监测系统，以错误相关负波（ERN）为指标，该负波与内心言语监测有关。在图片命名过程中，对11名患有pLTC损伤的个体（脑电图分析中包括来自两个机构的各4名）、7名pLTC未受损的个体（包括6名）和20名匹配的对照组（包括14名）进行了脑电图记录。患有pLTC损伤的个体比其他组速度更慢且准确性更低。pLTC未受损的个体表现出预期的ERN；而患有pLTC损伤的个体则没有。因此，当词汇提取的核心区域受损时，内侧额叶监测机制可能会受到损害，这表明pLTC-内侧额叶的相互作用可能支持内心言语监测。
