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用于中医辨证的双通道知识注意力机制

Dual-channel knowledge attention for traditional Chinese medicine syndrome differentiation.

作者信息

Liu Boting, Huang Hengqiu, Liu Xiaoman, Zhao Juntao, Mo Jiean

机构信息

School of Mathematics and Computer Science, Guangxi Minzu Normal University, Chongzuo, 532200, China.

出版信息

Sci Rep. 2025 Apr 18;15(1):13487. doi: 10.1038/s41598-025-96404-w.

DOI:10.1038/s41598-025-96404-w
PMID:40251192
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12008396/
Abstract

With the rapid advancement of Natural Language Processing (NLP) technologies, the application of NLP to enable intelligent syndrome differentiation in Traditional Chinese Medicine (TCM) has become a popular research focus. However, TCM texts contain numerous obscure characters and specialized terminologies, which existing methods struggle to effectively extract, leading to lower accuracy in syndrome differentiation. To address this, we propose a dual-channel knowledge-attention model for TCM syndrome differentiation. The model utilizes the ZY-BERT, a large pre-trained model in the TCM domain, to extract vector representations of TCM texts. A dual-channel network, comprising an improved Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) network, is employed to capture both critical local information and global patterns in TCM texts. Additionally, an attention mechanism is introduced to enhance the model's ability to learn syndrome-related knowledge, integrating syndrome definition knowledge to improve the model's ability to differentiate complex syndromes. Experiments conducted on a publicly available TCM syndrome differentiation dataset demonstrate that the proposed model achieves an accuracy of 84.01%, representing an 1.75% improvement in accuracy compared to the best baseline model.

摘要

随着自然语言处理(NLP)技术的快速发展,将NLP应用于中医智能辨证已成为热门研究焦点。然而,中医文本包含大量生僻字和专业术语,现有方法难以有效提取,导致辨证准确率较低。为解决这一问题,我们提出了一种用于中医辨证的双通道知识注意力模型。该模型利用中医领域的大型预训练模型ZY-BERT来提取中医文本的向量表示。采用由改进的卷积神经网络(CNN)和长短期记忆(LSTM)网络组成的双通道网络,以捕捉中医文本中的关键局部信息和全局模式。此外,引入注意力机制以增强模型学习证候相关知识的能力,整合证候定义知识以提高模型辨别复杂证候的能力。在公开可用的中医辨证数据集上进行的实验表明,所提出的模型准确率达到84.01%,与最佳基线模型相比,准确率提高了1.75%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b95/12008396/2883c45e2ed7/41598_2025_96404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b95/12008396/55a234cef924/41598_2025_96404_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b95/12008396/2883c45e2ed7/41598_2025_96404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b95/12008396/55a234cef924/41598_2025_96404_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b95/12008396/2883c45e2ed7/41598_2025_96404_Fig2_HTML.jpg

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本文引用的文献

1
TLDA: A transfer learning based dual-augmentation strategy for traditional Chinese Medicine syndrome differentiation in rare disease.TLDA:一种基于迁移学习的双重增强策略,用于罕见病中医证候分类。
Comput Biol Med. 2024 Feb;169:107808. doi: 10.1016/j.compbiomed.2023.107808. Epub 2023 Dec 5.
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Advances in the Application of Traditional Chinese Medicine Using Artificial Intelligence: A Review.人工智能在中医药应用中的进展:综述。
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Combining the External Medical Knowledge Graph Embedding to Improve the Performance of Syndrome Differentiation Model.
结合外部医学知识图谱嵌入以提高辨证模型的性能。
Evid Based Complement Alternat Med. 2023 Feb 1;2023:2088698. doi: 10.1155/2023/2088698. eCollection 2023.
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Multi-Task Joint Learning Model for Chinese Word Segmentation and Syndrome Differentiation in Traditional Chinese Medicine.多任务联合学习模型在中医分词和证候分类中的应用
Int J Environ Res Public Health. 2022 May 5;19(9):5601. doi: 10.3390/ijerph19095601.
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J Am Med Inform Assoc. 2019 Dec 1;26(12):1632-1636. doi: 10.1093/jamia/ocz164.
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