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异位胰腺组织作为婴儿胃出口梗阻的罕见病因:一例报告

Heterotopic pancreatic tissue presenting as an unusual cause of gastric outlet obstruction in infancy: a case report.

作者信息

Oshiba Ahmed, Darweesh Karim, Sharafeldin Hend, Kotb Mostafa

机构信息

Pediatric Surgery Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

Pathology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

出版信息

J Med Case Rep. 2025 Apr 18;19(1):179. doi: 10.1186/s13256-024-04941-1.

Abstract

BACKGROUND

Gastric outlet obstruction beyond the neonatal period is an extremely rare condition when other causes such as infantile hypertrophic pyloric stenosis, pyloric atresia, and antral diaphragm are ruled out. Herein, we present the case of a 2-month-old girl who presented with repeated nonbilious vomiting and showed ectopic pancreatic tissue compressing the pylorus of the stomach.

CASE PRESENTATION

A 2-month-old Caucasian girl who suffered from frequent attacks of projectile vomiting that was not resolved by medication presented to our institute. On ultrasonography, pyloric stenosis was excluded, while on gastrograffin study, there was a hugely dilated stomach with delayed passage of contrast to the distal bowel. On surgical exploration, there was an exophytic pyloric mass compressing the pyloric canal, which was completely excised. Pathological results confirmed the presence of heterotopic pancreatic tissue.

CONCLUSION

Heterotopic pancreas should always be considered as one of the rare differentials of the causes of gastric outlet obstruction in infants. Although many investigations such as sonogram and upper gastrointestinal series help in diagnosis, histology remains the definitive test in reaching the final diagnosis.

摘要

背景

排除诸如婴儿肥厚性幽门狭窄、幽门闭锁及胃窦隔膜等其他病因后,新生儿期以后出现的胃出口梗阻是一种极为罕见的病症。在此,我们报告一例2个月大的女孩,她反复出现非胆汁性呕吐,检查发现异位胰腺组织压迫胃幽门。

病例报告

一名2个月大的白种女孩因频繁发作喷射性呕吐且药物治疗无效前来我院就诊。超声检查排除了幽门狭窄,而胃肠造影检查显示胃极度扩张,造影剂向远端肠道的通过延迟。手术探查发现一个外生性幽门肿物压迫幽门管,遂将其完整切除。病理结果证实存在异位胰腺组织。

结论

异位胰腺应始终被视为婴儿胃出口梗阻病因中罕见的鉴别诊断之一。尽管超声检查和上消化道造影等多项检查有助于诊断,但组织学检查仍是做出最终诊断的决定性检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ccca/12008855/458aab6ea385/13256_2024_4941_Fig1_HTML.jpg

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