Hao Xiaojiao, Zhang Yan, Huang Damin, Gu Wenxi, Lu Yingmin
Department of Cardiology, Chongming Hospital, Shanghai University of Health & Medicine Sciences, Shanghai, China.
Heart Rehabilitation Center, Shanghai Tenth People's Hospital, Shanghai, China.
J Cardiothorac Surg. 2025 Apr 18;20(1):210. doi: 10.1186/s13019-024-03230-8.
OBJECTIVE: To observe, compare and explore the effect of enhanced extracorporeal counterpulsation (EECP) treatment on cardiac rehabilitation in patients with acute myocardial infarction (AMI) after undergoing percutaneous coronary intervention (PCI) using a drug-coated balloon (DCB). METHODS: This study was a prospective randomised controlled trial of 60 patients with AMI after undergoing PCI using a DCB. Using a random number table method, the patients were randomly divided into control and rehabilitation groups, with 30 patients in each. The follow-up period was 6 months. Patients in the control group received conventional drug and exercise rehabilitation after undergoing DCB-based PCI; those in the rehabilitation group were also given an EECP-based rehabilitation regimen after 7 days of medication and exercise rehabilitation. The effects of EECP on the rehabilitation of patients with AMI after undergoing DCB-based PCI were evaluated by observing changes in cardiac function before and after treatment in the two groups of patients, including cardiac output (CO), stroke volume (SV), brain natriuretic peptide (BNP), left ventricular ejection fraction (LVEF) and 6-minute walking distance (6MWD). RESULTS: After 6 months of treatment, the control versus the rehabilitation groups' cardiac function results were as follows: CO (5.00 ± 0.67 vs. 4.64 ± 0.58, P = 0.023), SV (70.53 ± 3.33 vs. 65.57 ± 6.10, P < 0.001), BNP (157.63 ± 15.37 vs. 219.40 ± 16.73, P < 0.001), LVEF (65.57 ± 4.33 vs. 60.10 ± 2.92, P < 0.001) and 6MWD (455.43 ± 39.75 vs. 400.73 ± 36.81, P < 0.001). The patients in the rehabilitation group showed improved cardiac function compared with the control group, with statistically significant differences. Furthermore, the improvement in the New York Heart Association cardiac function grading (P < 0.001) and Canadian Cardiovascular Association angina grading (P < 0.001) in the rehabilitation group were significantly improved compared with the gradings of the control group. CONCLUSION: Using EECP treatment significantly improved the cardiac function of patients with AMI after undergoing DCB-based PCI and was beneficial for their cardiac rehabilitation.
目的：观察、比较并探讨强化体外反搏（EECP）治疗对急性心肌梗死（AMI）患者经皮冠状动脉介入治疗（PCI）后使用药物涂层球囊（DCB）进行心脏康复的效果。 方法：本研究为前瞻性随机对照试验，纳入60例AMI患者，均接受了DCB辅助的PCI治疗。采用随机数字表法，将患者随机分为对照组和康复组，每组30例。随访期为6个月。对照组患者在接受DCB辅助的PCI治疗后接受常规药物和运动康复；康复组患者在药物和运动康复7天后还接受了基于EECP的康复方案。通过观察两组患者治疗前后的心功能变化，包括心输出量（CO）、每搏输出量（SV）、脑钠肽（BNP）、左心室射血分数（LVEF）和6分钟步行距离（6MWD），评估EECP对AMI患者DCB辅助PCI后康复的影响。 结果：治疗6个月后，对照组与康复组的心功能结果如下：CO（5.00±0.67 vs. 4.64±0.58，P = 0.023），SV（70.53±3.33 vs. 65.57±6.10，P < 0.001），BNP（157.63±15.37 vs. 219.40±16.73，P < 0.001），LVEF（65.57±4.33 vs. 60.10±2.92，P < 0.001）和6MWD（455.43±39.75 vs. 400.73±36.81，P < 0.001）。与对照组相比，康复组患者的心功能有所改善，差异具有统计学意义。此外，康复组的纽约心脏协会心功能分级（P < 0.001）和加拿大心血管协会心绞痛分级（P < 0.001）较对照组有显著改善。 结论：使用EECP治疗可显著改善AMI患者DCB辅助PCI后的心脏功能，有利于其心脏康复。
Ont Health Technol Assess Ser. 2006
Curr Cardiol Rep. 2023-10
Cardiovasc Revasc Med. 2023-11
Int Anesthesiol Clin. 2022-10-1
Anatol J Cardiol. 2022-5
Front Cardiovasc Med. 2021-12-14
Zotero 插件