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腹主动脉瘤血管内修复术的局部麻醉与全身麻醉:一项系统评价和荟萃分析

Local Versus General Anesthesia for Endovascular Repair of Abdominal Aortic Aneurysm: A Systematic Review and Meta-analysis.

作者信息

Sobreira Luis Eduardo Rodrigues, Costa Marilia Pereira, Dantas Clara Rocha, Silva Anna Lydia Machado, Moraes Altino Ono

机构信息

Federal University of Pará, Altamira, Pará, Brazil.

Federal University of Pará, Altamira, Pará, Brazil.

出版信息

J Cardiothorac Vasc Anesth. 2025 Aug;39(8):2184-2192. doi: 10.1053/j.jvca.2025.03.036. Epub 2025 Mar 26.

Abstract

BACKGROUND

Endovascular aneurysm repair (EVAR) has become increasingly popular compared with open repair due to its minimally invasive approach for treating abdominal aortic aneurysms (AAAs). However, the ideal anesthetic choice for patients undergoing EVAR remains debated. While some advocate for local anesthesia (LA), others believe that general anesthesia (GA) offers certain advantages.

OBJECTIVE

To compare LA with GA in patients undergoing EVAR.

METHODS

A search was conducted in the PubMed, Scopus, Embase, and Cochrane databases, focusing on studies that compared postoperative outcomes. Data were pooled using fixed- or random-effects models, and results are given in mean differences (MDs) and odds ratios (ORs) with 95% confidence intervals (CIs). Heterogeneity was calculated using the I statistic. All statistical analyses were performed using R software.

RESULTS

A total of 16 studies were included, comprising 45,566 patients. LA was associated with a decline in total hospital stay (MD: -1.00 day, 95% CI: -1.38 to -0.63, p < 0.01), myocardial infarction (OR: 0.52, 95% CI: 0.29 to 0.93, p = 0.02), and pneumonia (OR: 0.25, 95% CI: 0.11 to 0.55, p < 0.01). The LA group had an insignificant association with lower incidence of mortality (OR: 0.85, 95% CI: 0.64 to 1.13, p = 0.26) and in intensive care unit length of stay (MD: -0.20 day, 95% CI: -0.47 to 0.07, p = 0.14).

CONCLUSION

These results indicate that patients treated with LA are likely to be discharged more quickly and experience fewer adverse events.

摘要

背景

与开放修复相比,血管内动脉瘤修复术(EVAR)因其治疗腹主动脉瘤(AAA)的微创方法而越来越受欢迎。然而,接受EVAR治疗的患者的理想麻醉选择仍存在争议。虽然一些人主张局部麻醉(LA),但另一些人认为全身麻醉(GA)有一定优势。

目的

比较接受EVAR治疗的患者中局部麻醉与全身麻醉的效果。

方法

在PubMed、Scopus、Embase和Cochrane数据库中进行检索,重点关注比较术后结果的研究。使用固定效应或随机效应模型汇总数据,结果以平均差(MDs)和比值比(ORs)及95%置信区间(CIs)表示。使用I统计量计算异质性。所有统计分析均使用R软件进行。

结果

共纳入16项研究,涉及45566例患者。局部麻醉与总住院时间缩短(MD:-1.00天,95%CI:-1.38至-0.63,p<0.01)、心肌梗死(OR:0.52,95%CI:0.29至0.93,p = 0.02)和肺炎(OR:0.25,95%CI:0.11至0.55,p<0.01)相关。局部麻醉组与较低的死亡率(OR:0.85,95%CI:0.64至1.13,p = 0.26)和重症监护病房住院时间(MD:-0.20天,95%CI:-0.47至0.07,p = 0.14)发生率无显著关联。

结论

这些结果表明,接受局部麻醉治疗的患者可能出院更快,不良事件更少。

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