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制定用于对因谵妄入院的老年患者进行促发因素系统筛查的检查表。

Development of a checklist for systematic screening of precipitating factors in older patients admitted to hospital with delirium.

作者信息

Lafuente-Lafuente Carmelo, Candia Evany Heinichen, Pautas Eric, Freund Yonathan, Oquendo Bruno, Belmin Joël

机构信息

Hôpital Charles Foix, Service de Gériatrie à orientation Cardiologique et Neurologique, Sorbonne Université, APHP, 7 avenue de la République, 94205, Ivry-sur-Seine, France.

Clinical Epidemiology and Ageing (CEpiA) Team, Université Paris Est Créteil, INSERM, IRMB, 94000, Créteil, France.

出版信息

Eur Geriatr Med. 2025 Apr 20. doi: 10.1007/s41999-025-01191-2.

Abstract

OBJECTIVES

Causes of delirium are often multiple in older people and a significant number of them are missed at the initial assessment. We wanted to develop a checklist to help clinicians to systematically screen for the most frequent and important causes of delirium in this population.

METHODS

Three investigators, based on previous studies, drafted three possible checklist base models, comprising 18-29 items. A panel of 12 experts voted to choose one of the models, and then followed a modified Delphi consensus method to review each item and further develop the checklist. The consensus checklist was then tested in a small group of patients. The target population was older patients with delirium arriving to the emergency department or to a medical hospital ward.

RESULTS

The longest of the three drafts was unanimously chosen by the panel. After three rounds, a consensus was reached and a final checklist agreed. It is composed by 27 items organized in five groups of causes: infections, hydro-electrolytic disturbances, drugs, acute neurological conditions, and other acute diseases. A pilot study conducted by 15 physicians in 21 consecutive patients showed that the checklist was easy to complete, quick (mean 4 min) and most clinicians, though it helped them through the initial diagnostic work.

CONCLUSIONS

We have developed and pilot tested a checklist for screening for acute precipitants of delirium in older patients, aimed to facilitate early recognition and treatment of the multiple causes that often coexists in this population.

摘要

目的

老年人谵妄的病因往往是多方面的,其中相当一部分在初始评估时被遗漏。我们希望制定一份清单,以帮助临床医生系统地筛查该人群中谵妄最常见和最重要的病因。

方法

三名研究人员根据先前的研究起草了三个可能的清单基础模型,包含18 - 29项。由12名专家组成的小组投票选出其中一个模型,然后采用改良的德尔菲共识方法对每个项目进行审查并进一步完善清单。随后在一小群患者中对这份达成共识的清单进行测试。目标人群是前往急诊科或内科病房的老年谵妄患者。

结果

小组一致选择了三份草稿中最长的那份。经过三轮讨论,达成了共识并确定了最终清单。它由27项组成,分为五组病因:感染、水电解质紊乱、药物、急性神经系统疾病和其他急性疾病。15名医生对21例连续患者进行的一项初步研究表明,该清单易于填写,耗时短(平均4分钟),并且对大多数临床医生有帮助,能辅助他们完成初步诊断工作。

结论

我们已经制定并初步测试了一份用于筛查老年患者谵妄急性诱发因素的清单,旨在促进对该人群中经常并存的多种病因的早期识别和治疗。

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