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老年急诊患者谵妄患病率的系统评价和荟萃分析。

Delirium prevalence in geriatric emergency department patients: A systematic review and meta-analysis.

机构信息

Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China; Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.

Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, China.

出版信息

Am J Emerg Med. 2022 Sep;59:121-128. doi: 10.1016/j.ajem.2022.05.058. Epub 2022 Jul 1.

DOI:10.1016/j.ajem.2022.05.058
PMID:35841845
Abstract

BACKGROUND

In the emergency department, delirium associated with serious adverse outcomes is common in geriatric patients. We performed a meta-analysis and estimated the prevalence of delirium and its related factors among geriatric emergency department patients.

METHODS

PubMed, Embase, Web of Science, Cochrane Library, CINAHL, PsycINFO, and CBM databases were searched before November 7, 2021. The random-effects model was used to estimate the prevalence of delirium. In addition, subgroup analyses were performed based on continent or region, publication year, age, sample size, and diagnostic criteria or assessment methods.

RESULTS

30 studies involving 19,534 geriatric patients in the emergency department were included. The overall pooled crude prevalence estimate of delirium was 15.2% [95% confidence interval (CI) 12.5-18.0%]. Subgroup analyses revealed that the region, publication year, age, sample size, and delirium assessment methods were significantly correlated with the prevalence of delirium. Meta-regression analysis showed that the publication year was positively, while the sample size was negatively associated with the pooled prevalence of delirium.

CONCLUSION

In the emergency department, delirium is common in geriatric patients. We should pay specific attention to delirium screening, prevention, and treatment in geriatric patients. Overall appropriate interventions should be utilized to reduce the occurrence of delirium and the adverse outcomes.

摘要

背景

在急诊科,老年患者中与严重不良结局相关的谵妄很常见。我们进行了一项荟萃分析,估计了急诊科老年患者中谵妄的患病率及其相关因素。

方法

检索了 2021 年 11 月 7 日前的 PubMed、Embase、Web of Science、Cochrane 图书馆、CINAHL、PsycINFO 和 CBM 数据库。使用随机效应模型来估计谵妄的患病率。此外,还根据大陆或地区、出版年份、年龄、样本量以及诊断标准或评估方法进行了亚组分析。

结果

纳入了 30 项涉及急诊科 19534 名老年患者的研究。谵妄的总体合并粗患病率估计值为 15.2%[95%置信区间(CI)12.5-18.0%]。亚组分析显示,地区、出版年份、年龄、样本量和谵妄评估方法与谵妄的患病率显著相关。Meta 回归分析表明,出版年份与合并的谵妄患病率呈正相关,而样本量与合并的谵妄患病率呈负相关。

结论

在急诊科,老年患者中谵妄很常见。我们应该特别注意对老年患者进行谵妄筛查、预防和治疗。应总体采用适当的干预措施,以降低谵妄的发生和不良结局。

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