Wan Ruihan, Huang Jie, Wang Kangle, Long Danting, Tao Aolong, Huang Jia, Liu Zhizhen
College of Rehabilitation Medicine Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
National-Local Joint Engineering Research Center of Rehabilitation Medicine Technology Fujian University of Traditional Chinese Medicine Fuzhou, Fujian, China.
J Cachexia Sarcopenia Muscle. 2025 Apr;16(2):e13806. doi: 10.1002/jcsm.13806.
Mind-body exercise (MBE) has shown promise in mitigating the effects of sarcopenia and frailty in older adults. Nevertheless, its effectiveness in enhancing muscle function and physical performance in this population has not been well established. This study aimed to investigate the effects of MBE on older adults with sarcopenia and frailty, to offer evidence-based exercise recommendations.
A comprehensive search for randomized controlled trials (RCTs) was conducted through multiple databases, including PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CINAHL, China National Knowledge Infrastructure (CNKI), WanFang, and Chinese Scientific Journals Full-Text Database (VIP), supplemented by manual reference searches from inception until February 2024. The eligible RCTs compared MBE with passive or active exercise controls, focusing on muscle function and physical performance in older adults aged 60 years or above. Subgroup analyses were conducted to evaluate the types, duration, and frequency of MBE.
Nine eligible RCTs with 1838 participants were included in this study. MBE demonstrated significant improvements compared with passive control, particularly in grip strength (WMD [weighted mean difference] = 0.99; 95% CI [95% confidence interval] = 0.06, 1.92; I = 3%, p = 0.04), Timed Up and Go Test (TUGT) (WMD = -4.04; 95% CI = -5.54, -2.53; I = 12%, p < 0.01), and Berg Balance Scale (BBS) scores (WMD = 3.63; 95% CI = 0.38, 6.87; I = 0%, p = 0.03). Even when compared to active exercise training, improvements were still observed in TUGT and BBS (p < 0.001), with a trend toward improved grip strength (WMD = -2.20; 95% CI = -4.35, -0.04; p = 0.05). No positive effect on muscle mass was observed. Subgroup analysis indicated that MBE performed more than 5 times a week for a short or medium duration (4-24 weeks) could improve grip strength (p < 0.05). Moderate-frequency intervention over a short period in this population yielded greater improvements in gait speed and Chair Rise Test completion time (p < 0.05).
MBE can enhance muscle function and physical performance to some extent in older adults with sarcopenia and frailty, whether they are compared with passive or active exercise training. However, positive effects on muscle mass have not been observed. Future studies are warranted to compare it with well-designed active exercise training programs that match the exercise volume, to draw more definitive conclusions to support the notion that MBE yields comparable effects.
身心锻炼（MBE）已显示出减轻老年人肌肉减少症和虚弱影响的潜力。然而，其在增强该人群肌肉功能和身体表现方面的有效性尚未得到充分证实。本研究旨在调查MBE对患有肌肉减少症和虚弱的老年人的影响，以提供基于证据的运动建议。
通过多个数据库对随机对照试验（RCT）进行全面检索，包括PubMed、Embase、Cochrane图书馆、科学网、PsycINFO、CINAHL、中国知网（CNKI）、万方和中文科技期刊全文数据库（维普），并从创刊至2024年2月进行手动参考文献检索作为补充。符合条件的RCT将MBE与被动或主动运动对照进行比较，重点关注60岁及以上老年人的肌肉功能和身体表现。进行亚组分析以评估MBE的类型、持续时间和频率。
本研究纳入了9项符合条件的RCT，共1838名参与者。与被动对照相比，MBE显示出显著改善，特别是在握力方面（加权平均差[WMD]=0.99；95%置信区间[CI]=0.06，1.92；I²=3%，p=0.04）、计时起立行走测试（TUGT）（WMD=-4.04；95%CI=-5.54，-2.53；I²=12%，p<0.01）和伯格平衡量表（BBS）评分（WMD=3.63；95%CI=0.38，6.87；I²=0%，p=0.03）。即使与主动运动训练相比，TUGT和BBS也有改善（p<0.001），握力有改善趋势（WMD=-2.20；95%CI=-4.35，-0.04；p=0.05）。未观察到对肌肉量的积极影响。亚组分析表明，每周进行超过5次的短期或中期（4-24周）MBE可提高握力（p<0.05）。对该人群进行短期中等频率干预，步态速度和从椅子上起身测试完成时间有更大改善（p<0.05）。
无论与被动还是主动运动训练相比，MBE在患有肌肉减少症和虚弱的老年人中都能在一定程度上增强肌肉功能和身体表现。然而，未观察到对肌肉量的积极影响。未来有必要将其与设计良好且运动总量匹配的主动运动训练方案进行比较，以得出更明确的结论来支持MBE产生类似效果的观点。
Zotero 插件
