Sunder Amala, Khaled Hadi Yusuf, Alkhuzaei Noor Ammar, Jamal Bushaqer Nayla, Al Khalifa Haya Isa, Darwish Basma, Dayoub Nawal
From the Department of Obstetrics & Gynecology (Sunder, Bushaqer, Al khalifa,Darwish), Bahrain Defense Force Hospital, Riffa, Bahrain; (Hadi, Alkhuzaei), Royal College of Surgeons in Ireland, Busaiteen, and (Dayoub), Assisted Reproductive and Gynecology Centre, London.
Saudi Med J. 2025 Apr;46(4):378-387. doi: 10.15537/smj.2025.46.4.20240555.
To evaluate and compare pregnancy complications associated with varying maternal age groups.
A retrospective analysis of singleton pregnancy outcomes at Bahrain Defense Force Hospital from January to December 2022. The study population was divided into 4 age groups: <25 years, 25-29 years, 30-34 years, and ≥35 years. Data on demographics, maternal and fetal characteristics were collected, and statistical significance was set at <0.05. Univariate logistic regression was performed to analyze maternal and neonatal outcomes, adjusting for maternal factors.
The study included 2,972 women aged 17-55. Significant associations were found between maternal age and outcomes. Body mass index (BMI) was significantly linked to age (<0.01), with younger women having lower BMI. Gestational diabetes mellitus (GDM) was more common in women ≥35 years (11.5%) vs. those <25 years (6.6%, =0.027). Intrauterine growth restriction (IUGR) was more prevalent in the <25 years age group (=0.041).Logistic regression showed women 30-34 years had a lower risk of GDM compared to 25-29 years (odds ratio [OR]: 0.544, CI: 0.365-0.811), and women <25 years had a higher risk of preterm delivery (OR: 1.365, CI: 1.015-1.837).
Maternal age is an independent risk factor for various adverse outcomes. Younger women (<25) are at higher risk for preterm delivery and IUGR, while older women (≥35) have higher rates of GDM.
评估和比较不同孕产妇年龄组相关的妊娠并发症。
对2022年1月至12月在巴林国防军医院的单胎妊娠结局进行回顾性分析。研究人群分为4个年龄组:<25岁、25 - 29岁、30 - 34岁和≥35岁。收集了人口统计学、孕产妇和胎儿特征的数据,统计学显著性设定为<0.05。进行单因素逻辑回归分析孕产妇和新生儿结局,并对孕产妇因素进行校正。
该研究纳入了2972名年龄在17 - 55岁之间的女性。发现孕产妇年龄与结局之间存在显著关联。体重指数(BMI)与年龄显著相关(<0.01),年轻女性的BMI较低。妊娠糖尿病(GDM)在≥35岁的女性中更常见(11.5%),而在<25岁的女性中为6.6%(P = 0.027)。小于胎龄儿(IUGR)在<25岁年龄组中更普遍(P = 0.041)。逻辑回归显示,30 - 34岁的女性患GDM的风险低于25 - 29岁的女性(优势比[OR]:0.544,置信区间[CI]:0.365 - 0.811),<25岁的女性早产风险更高(OR:1.365,CI:1.015 - 1.837)。
孕产妇年龄是各种不良结局的独立危险因素。年轻女性(<25岁)早产和IUGR风险较高,而年长女性(≥35岁)GDM发生率较高。