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使用增材制造的骨膜下植入物和游离腓骨瓣对全上颌骨切除缺损进行一期重建:病例报告

Primary reconstruction of total maxillectomy defect with additively manufactured subperiosteal implant and fibula free flap: a case report.

作者信息

De Riu Giacomo, Biglio Andrea, Baj Alessandro, Maniaci Antonino, Lechien Jerome R, Vaira Luigi Angelo

机构信息

Maxillofacial Surgery Operative Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, Viale San Pietro 43B, Sassari, Italy.

Maxillofacial Surgery Operative Unit, University of Milan, Milan, Italy.

出版信息

Oral Maxillofac Surg. 2025 Apr 21;29(1):86. doi: 10.1007/s10006-025-01379-7.

Abstract

BACKGROUND

Total maxillectomy for malignant tumors presents significant challenges for functional and aesthetic rehabilitation. Advances in digital planning and additive manufacturing have reintroduced subperiosteal implants as a promising solution for primary reconstructions.

CASE REPORT

This report details the case of a 59-year-old male with squamous cell carcinoma of the hard palate extending contralaterally, treated with a total maxillectomy and primary reconstruction using an osteomyocutaneous fibula free flap combined with a custom-made, additively manufactured subperiosteal implant. Preoperative planning integrated craniofacial CT scans, dental impressions, and lower limb angiography to design both the implant and fibula cutting guides. The implant, fabricated via direct metal laser sintering, provided a stable framework for fibular segments and future prosthetic rehabilitation. At two years post-surgery, the patient remains disease-free, with no complications and fully functional prosthetic integration.

CONCLUSIONS

This case highlights the feasibility, adaptability, and potential benefits of additively manufactured implants in reconstructing total maxillectomy defects.

CLINICAL TRIAL NUMBER

N/A.

摘要

背景

恶性肿瘤的全上颌骨切除术在功能和美学修复方面面临重大挑战。数字规划和增材制造技术的进步使骨膜下植入物重新成为一期重建的一种有前景的解决方案。

病例报告

本报告详细介绍了一名59岁男性患者,其硬腭鳞状细胞癌已向对侧扩展,接受了全上颌骨切除术,并使用游离腓骨肌皮瓣联合定制的增材制造骨膜下植入物进行一期重建。术前规划整合了颅面部CT扫描、牙模和下肢血管造影,以设计植入物和腓骨切割导板。通过直接金属激光烧结制造的植入物为腓骨段和未来的假体修复提供了稳定的框架。术后两年,患者无疾病复发,无并发症,假体完全功能整合。

结论

本病例突出了增材制造植入物在重建全上颌骨切除术后缺损方面的可行性、适应性和潜在益处。

临床试验编号

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4196/12009777/3e4288e67296/10006_2025_1379_Fig1_HTML.jpg

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