De Cassai Alessandro, Zarantonello Francesco, Pistollato Elisa, Pettenuzzo Tommaso, Busetto Veronica, Sella Nicolò, Boscolo Annalisa
Department of Medicine - DIMED, Thoracic, Vascular Sciences, and Public Health, University of Padua, Padua, Italy.
Institute of Anaesthesia and Intensive Care, Padua, Italy.
Saudi J Anaesth. 2025 Apr-Jun;19(2):221-226. doi: 10.4103/sja.sja_132_25. Epub 2025 Mar 25.
The increasing global prevalence of obesity has significant implications for anesthesiologists, particularly in the context of regional anesthesia. Anesthesiologists face numerous challenges during anesthesia in obese patients, including compromised respiratory function, altered pharmacokinetics of local anesthetics, and difficulties in identifying anatomical landmarks. Obesity often leads to reduced respiratory reserve, increased risk of hypoventilation, and conditions such as obstructive sleep apnea syndrome and obesity hypoventilation syndrome, which increase the likelihood of postoperative complications. Additionally, altered body composition in obese patients affects the distribution of local anesthetics, requiring adjustments in dosing based on lean body weight rather than total body weight. Furthermore, excess adipose tissue complicates the identification of anatomical landmarks and the use of ultrasound for regional block procedures, as the increased tissue depth and reduced image resolution hinder needle placement. Proper positioning, the use of low-frequency transducers, and harmonic imaging techniques are essential for optimizing ultrasound guidance. Additionally, the use of longer needles and the application of trigonometric calculations based on ultrasound scans can help determine the appropriate needle length. To overcome these challenges, anesthesiologists should adopt strategies that involve adjusting drug dosages, utilizing specialized equipment, and continuously monitoring patients for potential complications. A holistic approach involving knowledge of these technical and pathological challenges, as well as adapting techniques and equipment, is crucial for ensuring the safety and effectiveness of regional anesthesia in obese patients.
全球肥胖患病率的不断上升对麻醉医生具有重大影响,尤其是在区域麻醉方面。麻醉医生在肥胖患者麻醉期间面临众多挑战,包括呼吸功能受损、局部麻醉药药代动力学改变以及识别解剖标志困难。肥胖常导致呼吸储备减少、通气不足风险增加以及诸如阻塞性睡眠呼吸暂停综合征和肥胖低通气综合征等情况,这增加了术后并发症的可能性。此外,肥胖患者身体成分的改变会影响局部麻醉药的分布,需要根据瘦体重而非总体重调整剂量。此外,过多的脂肪组织使解剖标志的识别以及超声在区域阻滞操作中的使用变得复杂,因为组织深度增加和图像分辨率降低会妨碍穿刺针的放置。正确的体位、使用低频换能器和谐波成像技术对于优化超声引导至关重要。此外,使用更长的穿刺针以及基于超声扫描应用三角计算可以帮助确定合适的穿刺针长度。为克服这些挑战,麻醉医生应采取包括调整药物剂量、使用专用设备以及持续监测患者有无潜在并发症等策略。一种综合方法,包括了解这些技术和病理挑战以及调整技术和设备,对于确保肥胖患者区域麻醉的安全性和有效性至关重要。