Celayir Arın, Elibollar Cansu, Demirdas Ahmet Burak, Sahin Erdem, Onenerk Ayse Mine, Botanlioglu Huseyin
Department of Orthopaedics and Traumatology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, TUR.
Department of Pathology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, TUR.
Cureus. 2025 Mar 19;17(3):e80854. doi: 10.7759/cureus.80854. eCollection 2025 Mar.
Low-grade chondrosarcomas are rare malignant cartilaginous tumors with slow growth and low metastatic potential. Bilateral involvement, especially in the proximal humerus, is an exceedingly rare presentation. This report discusses a 45-year-old female patient who presented with intermittent left shoulder pain and was subsequently found to have bilateral proximal humeral masses on imaging. Bilateral contrast-enhanced MRI suggested a diagnosis of enchondroma or low-grade chondrosarcoma. The patient underwent curettage and cementation, first on the left side, followed by the right side four months later. Pathological analysis of the left lesion confirmed low-grade chondrosarcoma. During the second surgery, a frozen section revealed atypical chondromatous cells, with final pathology also supporting the diagnosis of low-grade chondrosarcoma. This case underscores the importance of careful diagnostic evaluation, including imaging and histopathological assessment, to differentiate low-grade chondrosarcoma from enchondroma. The multidisciplinary approach facilitated timely treatment, emphasizing the efficacy of curettage and cementation in managing these rare bilateral lesions while preserving function.
低度恶性软骨肉瘤是一种罕见的恶性软骨肿瘤，生长缓慢，转移潜能低。双侧受累，尤其是近端肱骨受累，是一种极为罕见的表现。本报告讨论了一名45岁女性患者，该患者出现间歇性左肩疼痛，随后影像学检查发现双侧近端肱骨肿块。双侧对比增强磁共振成像提示诊断为内生软骨瘤或低度恶性软骨肉瘤。患者先接受了左侧的刮除植骨术，四个月后又接受了右侧的手术。左侧病变的病理分析证实为低度恶性软骨肉瘤。在第二次手术中，冰冻切片显示非典型软骨瘤细胞，最终病理结果也支持低度恶性软骨肉瘤的诊断。该病例强调了仔细的诊断评估的重要性，包括影像学和组织病理学评估，以区分低度恶性软骨肉瘤和内生软骨瘤。多学科方法促进了及时治疗，强调了刮除植骨术在处理这些罕见的双侧病变并保留功能方面的有效性。
