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别携带害虫:密歇根州西南部的圭亚那利什曼原虫

Don't Pack a Pest: Leishmania Guyanensis in Southwest Michigan.

作者信息

Campbell Samantha M, Furlan Alan, Dellatorre Diniz Bruna, Costa Filho Francisco F, Boamah Harry

机构信息

Internal Medicine, Western Michigan University, Kalamazoo, USA.

Infectious Disease, Western Michigan University, Kalamazoo, USA.

出版信息

Cureus. 2025 Mar 21;17(3):e80956. doi: 10.7759/cureus.80956. eCollection 2025 Mar.


DOI:10.7759/cureus.80956
PMID:40255770
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12009603/
Abstract

Leishmaniasis is a protozoal infection that is typically transmitted through the saliva of a female Phlebotomine sandfly and can result in devastating mucocutaneous infections if not identified and treated quickly. Here we present a case of cutaneous in a 49-year-old woman who had recently gone on a trip to Costa Rica and was unaware of any bites she may have sustained while being there. The patient initially presented with a facial rash and was seen by both her primary care physician and dermatology before receiving a referral to infectious disease. After a prolonged work-up, during which she was given antibiotics and steroids, skin biopsy was able to confirm the diagnosis of , and she was started on a four-week course of miltefosine with complete resolution of her rash.

摘要

利什曼病是一种原生动物感染,通常通过雌性白蛉的唾液传播,如果不迅速识别和治疗,可能会导致毁灭性的皮肤黏膜感染。在此,我们报告一例49岁女性的皮肤利什曼病病例,该女性最近去哥斯达黎加旅行,并未意识到自己在当地可能遭受过任何叮咬。患者最初出现面部皮疹,在被转诊至传染病科之前,其初级保健医生和皮肤科医生都对她进行了诊治。经过长时间的检查,在此期间她接受了抗生素和类固醇治疗,皮肤活检最终确诊为利什曼病,随后她开始接受为期四周的米替福新治疗,皮疹完全消退。

相似文献

[1]
Don't Pack a Pest: Leishmania Guyanensis in Southwest Michigan.

Cureus. 2025-3-21

[2]
Interventions for American cutaneous and mucocutaneous leishmaniasis.

Cochrane Database Syst Rev. 2020-8-27

[3]
Leishmania (Viannia) guyanensis Causing Localized Cutaneous Leishmaniasis in a Traveler.

Cureus. 2022-7-20

[4]
First Molecular Report of () and () in Paraguayan Inhabitants Using High-Resolution Melt-PCR.

Am J Trop Med Hyg. 2019-10

[5]
Raising the suspicion of a non-autochthonous infection: identification of Leishmania guyanensis from Costa Rica exhibits a Leishmaniavirus related to Brazilian north-east and French Guiana viral genotypes.

Mem Inst Oswaldo Cruz. 2023

[6]
Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy.

BMC Infect Dis. 2017-7-7

[7]
Disseminated cutaneous leishmaniasis due to Leishmania guyanensis: case of a patient with 425 lesions.

Am J Trop Med Hyg. 2004-11

[8]
Cutaneous leishmaniasis by a needlestick injury, an occupational infection?

PLoS Negl Trop Dis. 2023-3

[9]
Case Report: Successful Treatment with Miltefosine of Severe New World Mucosal Leishmaniasis Caused by .

Am J Trop Med Hyg. 2020-6-4

[10]
Presence of Leishmania RNA Virus 1 in Leishmania guyanensis Increases the Risk of First-Line Treatment Failure and Symptomatic Relapse.

J Infect Dis. 2016-1-1

本文引用的文献

[1]
Leishmania (Viannia) guyanensis Causing Localized Cutaneous Leishmaniasis in a Traveler.

Cureus. 2022-7-20

[2]
Cutaneous and Mucocutaneous Leishmaniasis.

Actas Dermosifiliogr (Engl Ed). 2021-5-11

[3]
Cutaneous leishmaniasis successfully treated with miltefosine.

Cutis. 2020-10

[4]
Mucosal leishmaniasis: A forgotten disease, description and identification of species in 50 Colombian cases.

Biomedica. 2019-8-1

[5]
Leishmania (Viannia) guyanensis in tegumentary leishmaniasis.

Pathog Dis. 2018-6-1

[6]
Mechanism of Action of Miltefosine on Leishmania donovani Involves the Impairment of Acidocalcisome Function and the Activation of the Sphingosine-Dependent Plasma Membrane Ca Channel.

Antimicrob Agents Chemother. 2017-12-21

[7]
Cutaneous leishmaniasis: an emerging infectious disease in travelers.

Cutis. 2015-10

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