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Adenosine Makes a Scene.

作者信息

Scharfman Helen E

机构信息

Departments of Child & Adolescent Psychiatry, Neuroscience & Physiology, and Psychiatry, New York University Grossman School of Medicine and the Center for Dementia Research, The Nathan S. Kline Institute for Psychiatric Research.

出版信息

Epilepsy Curr. 2025 Apr 16;25(3):198-200. doi: 10.1177/15357597251323126. eCollection 2025 May-Jun.

DOI:10.1177/15357597251323126
PMID:40256115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12003313/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c895/12214361/46e900356ed1/10.1177_15357597251323126-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c895/12214361/46e900356ed1/10.1177_15357597251323126-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c895/12214361/46e900356ed1/10.1177_15357597251323126-fig1.jpg

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本文引用的文献

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Retrograde adenosine/A receptor signaling facilitates excitatory synaptic transmission and seizures.逆行腺苷 A 受体信号促进兴奋性突触传递和癫痫发作。
Cell Rep. 2024 Jul 23;43(7):114382. doi: 10.1016/j.celrep.2024.114382. Epub 2024 Jun 19.
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Contributions of Adult-Generated Granule Cells to Hippocampal Pathology in Temporal Lobe Epilepsy: A Neuronal Bestiary.成年生成的颗粒细胞对颞叶癫痫海马病理的贡献：一部神经元众生相
Brain Plast. 2018 Aug 10;3(2):169-181. doi: 10.3233/BPL-170056.
3
Adenosine A receptor and ecto-5'-nucleotidase/CD73 are upregulated in hippocampal astrocytes of human patients with mesial temporal lobe epilepsy (MTLE).
腺苷A受体和胞外5'-核苷酸酶/CD73在患有内侧颞叶癫痫（MTLE）的人类患者的海马星形胶质细胞中上调。
Purinergic Signal. 2016 Dec;12(4):719-734. doi: 10.1007/s11302-016-9535-2. Epub 2016 Sep 20.
4
Adenosine A2A receptor deficient mice are partially resistant to limbic seizures.腺苷A2A受体缺陷型小鼠对边缘叶癫痫具有部分抗性。
Naunyn Schmiedebergs Arch Pharmacol. 2009 Sep;380(3):223-32. doi: 10.1007/s00210-009-0426-8. Epub 2009 Jun 2.
5
Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy.产后神经发生作为颞叶癫痫的治疗靶点
Epilepsy Res. 2009 Aug;85(2-3):150-61. doi: 10.1016/j.eplepsyres.2009.03.006. Epub 2009 Apr 14.
6
Brain-derived neurotrophic factor mRNA and protein are targeted to discrete dendritic laminas by events that trigger epileptogenesis.脑源性神经营养因子信使核糖核酸和蛋白质通过引发癫痫发生的事件被靶向运输到离散的树突层。
J Neurosci. 2004 Jul 28;24(30):6842-52. doi: 10.1523/JNEUROSCI.5471-03.2004.
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Anterograde transport of neurotrophin proteins in the CNS--a reassessment of the neurotrophic hypothesis.神经营养蛋白在中枢神经系统中的顺行运输——对神经营养假说的重新评估。
Rev Neurosci. 1998;9(2):91-103. doi: 10.1515/revneuro.1998.9.2.91.
8
Effects of repeated administration of selective adenosine A1 and A2A receptor agonists on pentylenetetrazole-induced convulsions in the rat.重复给予选择性腺苷A1和A2A受体激动剂对大鼠戊四氮诱发惊厥的影响。
Eur J Pharmacol. 1995 Dec 29;294(2-3):383-9. doi: 10.1016/0014-2999(95)00557-9.
9
Adenosine: a potential mediator of seizure arrest and postictal refractoriness.腺苷：癫痫发作停止和发作后难治性的潜在介质。
Ann Neurol. 1992 Nov;32(5):618-24. doi: 10.1002/ana.410320504.