Nossen J
MMW Munch Med Wochenschr. 1977 Feb 4;119(5):159-62.
Segontin-Digoxin and digoxin were tested in a cross-over double blind trial in 30 patients with coronary heart disease and concomitant organic insufficiency in a cardiological specialist practice. As far as the coronary symptoms were concerned, treatment with Segontin-Digoxin was clearly superior to digoxin therapy alone. With regard to the elimination or improvement of signs of myocardial insufficiency, no difference could be established between the two preparations. A distinct lowering of heart rate and blood pressure, especially in hypertensives, was observed with Segontin-Digoxin therapy compared with digoxin alone.
在一家心脏病专科诊所，对30名患有冠心病并伴有器质性心功能不全的患者进行了交叉双盲试验，比较了西格汀地高辛（Segontin-Digoxin）和地高辛。就冠心病症状而言，西格汀地高辛治疗明显优于单独使用地高辛治疗。关于心肌功能不全体征的消除或改善，两种制剂之间未发现差异。与单独使用地高辛相比，使用西格汀地高辛治疗可观察到心率和血压明显降低，尤其是高血压患者。
