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[Segontin-地高辛用于冠心病的双盲研究结果(作者译)]

[Results of a double blind study with Segontin-Digoxin in coronary heart disease (author's transl)].

作者信息

Nossen J

出版信息

MMW Munch Med Wochenschr. 1977 Feb 4;119(5):159-62.

PMID:402569
Abstract

Segontin-Digoxin and digoxin were tested in a cross-over double blind trial in 30 patients with coronary heart disease and concomitant organic insufficiency in a cardiological specialist practice. As far as the coronary symptoms were concerned, treatment with Segontin-Digoxin was clearly superior to digoxin therapy alone. With regard to the elimination or improvement of signs of myocardial insufficiency, no difference could be established between the two preparations. A distinct lowering of heart rate and blood pressure, especially in hypertensives, was observed with Segontin-Digoxin therapy compared with digoxin alone.

摘要

在一家心脏病专科诊所,对30名患有冠心病并伴有器质性心功能不全的患者进行了交叉双盲试验,比较了西格汀地高辛(Segontin-Digoxin)和地高辛。就冠心病症状而言,西格汀地高辛治疗明显优于单独使用地高辛治疗。关于心肌功能不全体征的消除或改善,两种制剂之间未发现差异。与单独使用地高辛相比,使用西格汀地高辛治疗可观察到心率和血压明显降低,尤其是高血压患者。

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