鼻窦内翻性乳头状瘤的临床特征及复发预测因素：一项回顾性队列研究
Clinical characteristics and recurrence predictors of sinonasal inverted papilloma: a retrospective cohort study.
作者信息
Li XiangHua, Wang DongFei, Yin DeTao
机构信息
First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
出版信息
Front Oncol. 2025 Apr 7;15:1537905. doi: 10.3389/fonc.2025.1537905. eCollection 2025.
OBJECTIVE
To investigate the clinical characteristics and predictors of postoperative recurrence in sinonasal inverted papilloma (SNIP).
METHODS
A retrospective cohort study of 53 SNIP patients treated at Zhengzhou University Hospital (2019-2023) was conducted. Patients were stratified into primary (n=34) and recurrent (n=19) cohorts. Clinical variables were analyzed using univariate and multivariate logistic regression.
RESULTS
Smoking (OR=10.08, 95% CI=1.32-77.15), prior surgery (OR=17.26, 95% CI=2.69-110.76), and ipsilateral involvement (OR=7.79, 95% CI=1.05-57.99) emerged as independent recurrence predictors (P<0.05). Krouse staging (T3 vs. T1-T2) showed no significant association (P=0.198).
CONCLUSION
Comprehensive evaluation of smoking history, surgical history, and lesion laterality is critical for recurrence risk stratification in SNIP management.
目的
探讨鼻窦内翻性乳头状瘤（SNIP）的临床特征及术后复发的预测因素。
方法
对郑州大学医院2019年至2023年收治的53例SNIP患者进行回顾性队列研究。患者被分为初发组（n = 34）和复发组（n = 19）。采用单因素和多因素逻辑回归分析临床变量。
结果
吸烟（OR = 10.08，95%CI = 1.32 - 77.15）、既往手术史（OR = 17.26，95%CI = 2.69 - 110.76）和同侧受累（OR = 7.79，95%CI = 1.05 - 57.99）是独立的复发预测因素（P < 0.05）。Krouse分期（T3与T1 - T2）无显著相关性（P = 0.198）。
结论
全面评估吸烟史、手术史和病变侧别对于SNIP治疗中复发风险分层至关重要。
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