Zhang Ke-Rui, Yang Yi, Li Ya-Qin, Ma Li-Tai, Wang Bei-Yu, Ding Chen, Meng Yang, Rong Xin, Hong Ying, Liu Hao
Department of Orthopedic West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu , Sichuan, 610041, China.
School of Nursing, the Hongkong Polytechnic University, Hong Kong, China.
BMC Musculoskelet Disord. 2025 Apr 22;26(1):404. doi: 10.1186/s12891-025-08625-9.
Anterior cervical corpectomy and fusion (ACCF) with Traditional Titanium Mesh Cages (TTMCs) can lead to complications such as cage subsidence, dysphagia, and implant-related issues. These complications suggest that the biomechanical stability of ACCF with TTMC may be insufficient. This study aims to evaluate whether a New Assembled Titanium Mesh Cage (NTMC) can improve the biomechanical performance after ACCF.
ACCF procedures using both TTMC and NTMC models were constructed and compared. The range of motion (ROM) of the surgical segments and stress peaks in various regions including the endplate, bone-screw interface, facet joints, and adjacent intervertebral discs were analyzed.
The use of NTMC significantly reduced the postoperative ROM of the surgical segments by 80.7%-82.0% compared to ACCF with TTMC. Additionally, stress peaks at the endplate, bone-screw interface, and facet contact force (FCF) were higher in ACCF with TTMC compared to NTMC. TTMC also induced higher stress peaks in the C3/4 and C6/7 intervertebral discs (ranging from 0.2009-6.961 MPa and 0.2477-4.735 MPa, respectively), followed by the NTMC (ranging from 0.1322-3.820 MPa and 0.2227-4.104 MPa, respectively).
The utilization of NTMC, which includes enlarged spacers and emulates endplate geometries, effectively reduces the risks of cage subsidence and instrument-related complications in ACCF. Furthermore, ACCF with NTMC also decreases the risks of dysphagia, facet joint degeneration, and adjacent disc degeneration during the follow-up period by altering the fixing method while maintaining construct stability.
采用传统钛网笼(TTMC)进行颈椎前路椎体次全切除融合术(ACCF)可能会导致诸如笼体下沉、吞咽困难和植入物相关问题等并发症。这些并发症表明采用TTMC的ACCF的生物力学稳定性可能不足。本研究旨在评估新型组装钛网笼(NTMC)能否改善ACCF后的生物力学性能。
构建并比较使用TTMC和NTMC模型的ACCF手术过程。分析手术节段的活动范围(ROM)以及包括终板、骨螺钉界面、小关节和相邻椎间盘在内的各个区域的应力峰值。
与采用TTMC的ACCF相比,使用NTMC可使手术节段术后ROM显著降低80.7%-82.0%。此外,与NTMC相比,采用TTMC的ACCF在终板、骨螺钉界面的应力峰值以及小关节接触力(FCF)更高。TTMC还在C3/4和C6/7椎间盘中诱导出更高的应力峰值(分别为0.2009 - 6.961MPa和0.2477 - 4.735MPa),其次是NTMC(分别为0.1322 - 3.820MPa和0.2227 - 4.104MPa)。
采用包括扩大的间隔物并模拟终板几何形状的NTMC,可有效降低ACCF中笼体下沉和器械相关并发症的风险。此外,采用NTMC的ACCF通过改变固定方法同时保持结构稳定性,还可降低随访期间吞咽困难、小关节退变和相邻椎间盘退变的风险。