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一个家族内的多个微晶沉积。

Multiple microcrystal deposition within a family.

作者信息

Doherty M, Dieppe P A

出版信息

Ann Rheum Dis. 1985 Aug;44(8):544-8. doi: 10.1136/ard.44.8.544.

Abstract

A family is described in which four members in three generations showed evidence of crystal deposition disease: two developed calcium pyrophosphate dihydrate (CPPD) crystal deposition, one calcific periarthritis, and one mixed crystal deposition disease (gout + chondrocalcinosis). This previously undescribed observation supports a possible role for nonspecific heritable connective tissue factors in predisposing to crystal deposition.

摘要

本文描述了一个家族,三代人中的四名成员表现出晶体沉积病的迹象:两人患焦磷酸钙二水合物(CPPD)晶体沉积病,一人患钙化性关节炎,一人患混合性晶体沉积病(痛风+软骨钙质沉着症)。这一先前未被描述的观察结果支持了非特异性遗传性结缔组织因素在晶体沉积易感性中可能发挥的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7ab6/1001699/1ffb4c3813cb/annrheumd00263-0045-a.jpg

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