Chang Yi-Pin, Chen Hsin-Hua, Tseng Jui-Ju, Tsai Chia-I
Department of Traditional Chinese Medicine, Taichung Veterans General Hospital, Taiwan.
Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
Bone Rep. 2025 Apr 4;25:101842. doi: 10.1016/j.bonr.2025.101842. eCollection 2025 Jun.
Bone fracture is a common orthopedic condition that affects millions of people worldwide. The management frequently involves surgery, which requires hospitalization. Patients with fractures often have a risk of developing complications, including pain, inflammation, infection, delayed healing, thrombosis, and organ failure. Acupuncture is widely used for conditions such as pain, respiratory issues, urinary system disorders, and gastrointestinal discomfort.
In this retrospective study, we evaluated the effectiveness of acupuncture in reducing postoperative complications in fracture patients. Using the TriNetX platform, we identified individuals hospitalized for their first fracture surgery and performed 1: 1 propensity score matching. Patients who received three or more acupuncture treatments within one week ( = 433) were compared to those who received none (n = 433), with matching based on age, sex, race, BMI, comorbidities, and medications (standardized mean differences). Postoperative complications within 180 days were analyzed using risk percentages, risk ratios, odds ratios, Kaplan-Meier analysis with log-rank tests, and hazard ratios, all reported with 95 % confidence intervals and -values.
Fourteen patients in the acupuncture group experienced respiratory failure with a risk of 3.2 %, while 29 patients in the non-acupuncture group developed respiratory failure with a risk of 6.7 %. The risk ratio was 0.48 (95 % CI 0.26-0.90) and the OR was 0.47 (95 % CI 0.24-0.89). The Kaplan-Meier analysis found a significantly higher survival probability in the acupuncture group (log-rank test = 0.01; HR 0.44, 95%CI 0.23-0.83).
Acupuncture appeared to have the potential to reduce postoperative complications in bone fracture patients. Further large-scale studies are needed to provide stronger evidence.
骨折是一种常见的骨科疾病，影响着全球数百万人。其治疗通常需要手术，这就需要住院。骨折患者往往有发生并发症的风险，包括疼痛、炎症、感染、愈合延迟、血栓形成和器官衰竭。针灸广泛应用于疼痛、呼吸系统疾病、泌尿系统疾病和胃肠道不适等病症。
在这项回顾性研究中，我们评估了针灸在减少骨折患者术后并发症方面的有效性。利用TriNetX平台，我们确定了因首次骨折手术而住院的患者，并进行了1:1倾向评分匹配。将在一周内接受三次或更多次针灸治疗的患者（n = 433）与未接受针灸治疗的患者（n = 433）进行比较，匹配因素包括年龄、性别、种族、体重指数、合并症和用药情况（标准化均值差异）。使用风险百分比、风险比率、优势比、带有对数秩检验的Kaplan-Meier分析以及风险比，对180天内的术后并发症进行分析，所有结果均报告95%置信区间和P值。
针灸组有14名患者发生呼吸衰竭，风险为3.2%，而非针灸组有29名患者发生呼吸衰竭，风险为6.7%。风险比率为0.48（95%置信区间0.26 - 0.90），优势比为0.47（95%置信区间0.24 - 0.89）。Kaplan-Meier分析发现针灸组的生存概率显著更高（对数秩检验P = 0.01；风险比0.44，95%置信区间0.23 - 0.83）。
针灸似乎有降低骨折患者术后并发症的潜力。需要进一步的大规模研究来提供更有力的证据。
