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Rethinking treatment approaches for FIGO stage IVB cervical cancer: personalized strategies and emerging therapies.

作者信息

Zeng Jing, Yin Rutie

机构信息

Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, China.

Key Laboratory of Birth Defects and Related Diseases of Women and Children, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.

出版信息

Front Immunol. 2025 Apr 8;16:1567296. doi: 10.3389/fimmu.2025.1567296. eCollection 2025.

DOI:10.3389/fimmu.2025.1567296
PMID:40264775
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12011788/
Abstract
摘要

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Rethinking treatment approaches for FIGO stage IVB cervical cancer: personalized strategies and emerging therapies.重新思考国际妇产科联盟(FIGO)IVB期宫颈癌的治疗方法:个性化策略与新兴疗法
Front Immunol. 2025 Apr 8;16:1567296. doi: 10.3389/fimmu.2025.1567296. eCollection 2025.
2
The new FIGO 2023 staging reclassification of patients with FIGO 2009 Stage IVB endometrial cancer correlates to progression-free and overall survival outcomes.国际妇产科联盟(FIGO)2023年对2009年IVB期子宫内膜癌患者的分期重新分类与无进展生存期和总生存期结果相关。
Gynecol Oncol Rep. 2024 Oct 5;56:101527. doi: 10.1016/j.gore.2024.101527. eCollection 2024 Dec.
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J Gynecol Oncol. 2010 Jun;21(2):93-6. doi: 10.3802/jgo.2010.21.2.93. Epub 2010 Jun 30.
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Int J Gynecol Cancer. 2018 Mar;28(3):453-458. doi: 10.1097/IGC.0000000000001186.
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Gynecol Oncol. 2023 Aug;175:32-40. doi: 10.1016/j.ygyno.2023.05.069. Epub 2023 Jun 13.

本文引用的文献

1
Standard of care treatment for stage IVB cervical cancer: A systematic review and meta-analysis.IVB期宫颈癌的标准治疗:一项系统评价与荟萃分析
Gynecol Oncol. 2024 Dec;191:259-264. doi: 10.1016/j.ygyno.2024.10.023. Epub 2024 Oct 30.
2
Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial.阿替利珠单抗联合贝伐珠单抗和化疗治疗转移性、持续性或复发性宫颈癌(BEATcc):一项随机、开放标签、3 期临床试验。
Lancet. 2024 Jan 6;403(10421):31-43. doi: 10.1016/S0140-6736(23)02405-4. Epub 2023 Dec 1.
3
First-Line Pembrolizumab + Chemotherapy Versus Placebo + Chemotherapy for Persistent, Recurrent, or Metastatic Cervical Cancer: Final Overall Survival Results of KEYNOTE-826.一线帕博利珠单抗+化疗对比安慰剂+化疗用于持续性、复发性或转移性宫颈癌:KEYNOTE-826 的最终总生存结果。
J Clin Oncol. 2023 Dec 20;41(36):5505-5511. doi: 10.1200/JCO.23.00914. Epub 2023 Nov 1.
4
Definitive irradiation as a first treatment strategy for primary and metastatic sites of newly diagnosed IVB cervical cancer that presented with synchronous oligometastases.对新诊断的 IVB 期宫颈癌伴同步寡转移灶的原发病灶和转移灶,行根治性放疗作为初始治疗策略。
Radiat Oncol. 2023 Sep 26;18(1):159. doi: 10.1186/s13014-023-02320-6.
5
Definitive pelvic radiotherapy for patients with newly diagnosed stage IVB cervical cancer: a systematic review.根治性盆腔放疗用于新诊断的 IVB 期宫颈癌患者:系统评价。
Int J Gynecol Cancer. 2023 Jul 3;33(7):1057-1062. doi: 10.1136/ijgc-2023-004465.
6
Metastatic extent-specific prognosis of women with stage IVB cervical cancer: multiple versus single distant organ involvement.IVB 期宫颈癌转移范围特异性预后:多处与单一远处器官转移。
Arch Gynecol Obstet. 2023 Feb;307(2):533-540. doi: 10.1007/s00404-022-06611-3. Epub 2022 May 21.
7
Pembrolizumab for Persistent, Recurrent, or Metastatic Cervical Cancer.派姆单抗治疗持续性、复发性或转移性宫颈癌。
N Engl J Med. 2021 Nov 11;385(20):1856-1867. doi: 10.1056/NEJMoa2112435. Epub 2021 Sep 18.
8
Role of locoregional surgery in treating FIGO 2009 stage IVB cervical cancer patients: a population-based study.局部区域性手术在治疗 FIGO 2009 分期 IVB 期宫颈癌患者中的作用:一项基于人群的研究。
BMJ Open. 2021 Aug 11;11(8):e042364. doi: 10.1136/bmjopen-2020-042364.
9
Incorporation of whole pelvic radiation into treatment of stage IVB cervical cancer: A novel treatment strategy.将全骨盆放疗纳入 IVB 期宫颈癌治疗:一种新的治疗策略。
Gynecol Oncol. 2020 Jan;156(1):100-106. doi: 10.1016/j.ygyno.2019.10.033. Epub 2019 Dec 4.
10
Surgery of primary sites for stage IVB cervical cancer patients receiving chemoradiotherapy: a population-based study.同期放化疗的 IVB 期宫颈癌患者原发灶手术治疗:一项基于人群的研究。
J Gynecol Oncol. 2020 Jan;31(1):e8. doi: 10.3802/jgo.2020.31.e8. Epub 2019 Aug 2.