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试点研究:针对糖尿病足溃疡患者的创新性微创跗骨隧道松解术,将弊端降至最低。

Pilot Study: Innovative Minimally Invasive Tarsal Tunnel Release for Diabetic Foot Ulcer Patients Minimizing Drawbacks.

作者信息

Ngiam Hian Kim Erica, Png Wenxian, Cher Eric Wei Liang, Ch'ng Jack Kian, Wong Allen Wei Jiat, Kok Yee Onn, Feng Jiajun

机构信息

From the Department of Plastic, Reconstructive and Aesthetic Surgery, Sengkang General Hospital, Singapore.

Department of Orthopaedic Surgery, Sengkang General Hospital, Singapore.

出版信息

Plast Reconstr Surg Glob Open. 2025 Apr 21;13(4):e6719. doi: 10.1097/GOX.0000000000006719. eCollection 2025 Apr.

DOI:10.1097/GOX.0000000000006719
PMID:40264906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12011571/
Abstract

BACKGROUND

Diabetic foot ulcers are challenging to manage due to the multifactorial nature of the disease, with diabetic neuropathy being a primary contributing factor. Tarsal tunnel release has shown promise in restoring sensation, reducing ulcer recurrence through improved sensation, and enhancing microcirculation to promote ulcer healing. However, existing open and endoscopic techniques have notable limitations. This study introduces a novel minimally invasive tarsal tunnel release technique designed to address these shortcomings.

METHODS

A retrospective cohort study was conducted at Sengkang General Hospital, a tertiary care center. The control group comprised 22 consecutive patients who underwent open tarsal tunnel release, whereas the treatment group included 34 consecutive patients treated with the novel minimally invasive approach. All patients were followed up for a minimum of 3 months.

RESULTS

Both groups demonstrated comparable efficacy in improving sensation (100% versus 95.5%) and 2-point discrimination (88.2% versus 86.4%; = 0.19, = 0.83, respectively). However, the treatment group exhibited significantly shorter wound lengths (2.3 ± 0.26 versus 5.8 ± 0.72 cm; < 0.0001) and a faster wound healing duration (15 ± 5 versus 24 ± 17 d; = 0.0052). Additionally, the treatment group experienced no major wound complications compared with a 13.6% complication rate in the control group ( = 0.029).

CONCLUSIONS

This minimally invasive novel technique demonstrates similar efficacy in improving sensation while addressing the limitations of existing open and endoscopic methods. It offers significant advantages in terms of reduced wound size, faster healing, and lower complication rates.

摘要

背景

糖尿病足溃疡因疾病的多因素性质而难以管理,糖尿病神经病变是主要促成因素。跗管松解术在恢复感觉、通过改善感觉减少溃疡复发以及增强微循环以促进溃疡愈合方面已显示出前景。然而,现有的开放和内镜技术存在明显局限性。本研究引入了一种新型微创跗管松解技术以解决这些缺点。

方法

在三级护理中心樟宜综合医院进行了一项回顾性队列研究。对照组包括22例连续接受开放跗管松解术的患者,而治疗组包括34例连续接受新型微创方法治疗的患者。所有患者均随访至少3个月。

结果

两组在改善感觉(100%对95.5%)和两点辨别觉(88.2%对86.4%;分别为P = 0.19,P = 0.83)方面显示出相当的疗效。然而,治疗组的伤口长度明显更短(2.3±0.26对5.8±0.72 cm;P < 0.0001),伤口愈合持续时间更快(15±5对24±17天;P = 0.0052)。此外,治疗组未发生重大伤口并发症,而对照组的并发症发生率为13.6%(P = 0.029)。

结论

这种新型微创技术在改善感觉方面显示出相似的疗效,同时解决了现有开放和内镜方法的局限性。它在减小伤口大小、加快愈合和降低并发症发生率方面具有显著优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/797036675f17/gox-13-e6719-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/50cb3f0eb930/gox-13-e6719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/3c2c45591fcf/gox-13-e6719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/b814d4b6f4ca/gox-13-e6719-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/b689c1557767/gox-13-e6719-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/780321142356/gox-13-e6719-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/acf542cdcdf7/gox-13-e6719-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/ebeb3f097585/gox-13-e6719-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/90b1d1bb84f7/gox-13-e6719-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/797036675f17/gox-13-e6719-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/50cb3f0eb930/gox-13-e6719-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/3c2c45591fcf/gox-13-e6719-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/b814d4b6f4ca/gox-13-e6719-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/b689c1557767/gox-13-e6719-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/780321142356/gox-13-e6719-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/acf542cdcdf7/gox-13-e6719-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/ebeb3f097585/gox-13-e6719-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/90b1d1bb84f7/gox-13-e6719-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c64d/12011571/797036675f17/gox-13-e6719-g009.jpg

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本文引用的文献

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J Wound Care. 2024 Dec 2;33(12):926-932. doi: 10.12968/jowc.2023.0008.
2
Lower Extremity Nerve Decompression for Diabetic Peripheral Neuropathy: A Systematic Review and Meta-analysis.糖尿病周围神经病变的下肢神经减压术:一项系统评价与Meta分析
Plast Reconstr Surg Glob Open. 2022 Aug 18;10(8):e4478. doi: 10.1097/GOX.0000000000004478. eCollection 2022 Aug.
3
Author Correction: Effects of diabetes mellitus on the rate of carpal tunnel release in patients with carpal tunnel syndrome.
作者更正:糖尿病对腕管综合征患者腕管松解术发生率的影响。
Sci Rep. 2021 Aug 19;11(1):17166. doi: 10.1038/s41598-021-96729-2.
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Endoscopic tarsal tunnel syndrome surgery using the Universal Subcutaneous Endoscope system.使用通用皮下内窥镜系统进行内镜下跗管综合征手术。
Asia Pac J Sports Med Arthrosc Rehabil Technol. 2015 Nov 2;3:1-5. doi: 10.1016/j.asmart.2015.09.001. eCollection 2016 Jan.
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Diabetic Foot Ulcers and Their Recurrence.糖尿病足溃疡及其复发
N Engl J Med. 2017 Jun 15;376(24):2367-2375. doi: 10.1056/NEJMra1615439.
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Evaluation of peripheral microcirculation improvement of foot after tarsal tunnel release in diabetic patients by transcutaneous oximetry.经皮血氧测定法评估糖尿病患者跗管松解术后足部外周微循环的改善情况
Microsurgery. 2016 Jan;36(1):37-41. doi: 10.1002/micr.22378. Epub 2015 Jan 13.
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Prevention of ulceration, amputation, and reduction of hospitalization: outcomes of a prospective multicenter trial of tibial neurolysis in patients with diabetic neuropathy.预防溃疡、截肢和减少住院:前瞻性多中心糖尿病神经病变患者胫骨神经松解术试验的结果。
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The role of peripheral nerve surgery in diabetic limb salvage.周围神经外科在糖尿病肢体保全中的作用。
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