Fradis M, Podoshin L, Ben-David J, Reiner B
Arch Otolaryngol. 1985 Aug;111(8):491-3. doi: 10.1001/archotol.1985.00800100039001.
Intratympanic injection of lidocaine hydrochloride was used to alleviate distressing symptoms of tinnitus and vertigo in 28 patients with Meniere's disease. Of the 28 patients, 82% found an immediate improvement in vertigo, and there was an improvement in tinnitus in 67.8%. There was no change in complaints of tinnitus or vertigo in five patients with Meniere's disease who were each injected with a similar amount of saline into the middle ear, and who acted as a control group. An intratympanic injection of lidocaine alleviated the disabling symptoms of tinnitus and vertigo in some of the patients with Meniere's disease who had not reacted well to medical treatment. The procedure is without the hazards of the intravenous injection of lidocaine, and can be done by every otologist, even in clinic practice.
鼓室内注射盐酸利多卡因用于缓解28例梅尼埃病患者令人痛苦的耳鸣和眩晕症状。28例患者中,82%的患者眩晕症状立即得到改善,67.8%的患者耳鸣症状有所改善。有5例梅尼埃病患者作为对照组,向其中耳内分别注射等量生理盐水,其耳鸣或眩晕症状无变化。鼓室内注射利多卡因可缓解部分对药物治疗反应不佳的梅尼埃病患者的致残性耳鸣和眩晕症状。该操作不存在静脉注射利多卡因的风险,每位耳科医生均可进行,甚至在临床实践中也能做到。