Cummings C W, Trachy R E
Arch Otolaryngol. 1985 Sep;111(9):598-600. doi: 10.1001/archotol.1985.00800110076006.
The dependence of a transposed myocutaneous flap on its own vascular pedicle for survival is time-related. The number of days required to establish effective sustaining perfusion from the periphery was assessed. Based on flap perfusion with associated vascular compression as monitored by the laser Doppler and dermofluorometer, adequate perfusion levels occurred at days 7 to 10 in the pig panniculus carnosus myocutaneous flap. It was established that all flaps will survive independent of the vascular pedicle when the laser Doppler readings are above 40 mV and the dermofluorometric readings are above 20%. The establishment of this baseline information now allows for the investigation of pharmacologic manipulation of the blood flow to diminish the duration of dependence on the transposed vascular pedicle.
转位肌皮瓣依靠自身血管蒂存活与时间相关。评估了从外周建立有效持续灌注所需的天数。根据激光多普勒和皮肤荧光计监测的伴有血管压迫的皮瓣灌注情况,猪腹直肌肌皮瓣在第7至10天出现足够的灌注水平。已确定当激光多普勒读数高于40 mV且皮肤荧光计读数高于20%时,所有皮瓣均可独立于血管蒂存活。这一基线信息的建立现在允许研究对血流进行药物调控,以缩短对转位血管蒂的依赖持续时间。