一种强效的抗伤害性大麻素，在猴子身上缺乏阿片类替代特性。
A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys.
作者信息
Martin B R, Dewey W L, Aceto M D, Adams M D, Earnhardt J T, Carney J M
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Jan;16(1):187-90.
PMID:402685
Abstract
(-)-9-Nor-9beta-hydroxy-hexahydrocannabinol[(-)-9-nor-9beta-OH-HHC] produced hypotension and bradycardia in anesthetized dogs, was a potent antinociceptive agent in the mouse tail-flick and p-phenylquinone abdominal-stretching tests, but did not reverse the effects of morphine withdrawal in dependent monkeys.
摘要
（-）-9-去甲-9β-羟基-六氢大麻酚[（-）-9-去甲-9β-OH-HHC]在麻醉犬中可引起低血压和心动过缓，在小鼠甩尾试验和对苯二酚腹部伸展试验中是一种强效的抗伤害感受剂，但不能逆转依赖猴的吗啡戒断效应。
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