Li D J, Liang D, Shi J, Liu Y Y, Jin J, Shan B E, He Y T
Cancer Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Zhonghua Zhong Liu Za Zhi. 2025 Apr 23;47(4):316-321. doi: 10.3760/cma.j.cn112152-20240110-00017.
To understand the burden of cancer disease in Hebei Province in recent years and to analyze the change trend of cancer in Hebei Province from 2011 to 2020. The incidence and death data of cancer were collected from 38 cancer registries in Hebei Province during 2011-2020. The incidence (mortality) rate, standardized incidence (mortality) rate and composition ratio of each region, sex, and age were calculated respectively, and the incidence and death of major cancers in our province were summarized. The age-standardized morbidity (mortality) rates of China and the world population were calculated using the 2000 China standard population composition and Segi's world population composition respectively. Trend analysis of morbidity and mortality was performed and average annual percentage change (AAPC) was calculated. In 2020, the crude cancer incidence rate and the age-standardized morbidity rate of China was 229.36/100 000 and 147.06/100 000, respectively. An estimated 171 600 new cases were reported in the province. The crude cancer mortality rate and the age-standardized mortality rates of China was 146.38/100 000 and 85.33/100 000. The estimated number of deaths in the province is 108 900. In the cancer registration areas of Hebei Province, 84% of all cancer patients occurred in people 50 years of age and older. From 2011 to 2020, the incidence and mortality of cancer in Hebei Province showed a decreasing trend. The AAPC was -4.2% (＜0.001), which decreased from 206.61/100 000 in 2011 to 143.74/100 000 in 2020. The world standard mortality rate of cancer was 147.69/100 000 in 2011, and decreased to 84.79/100 000 in 2020. The AAPC was -5.7% (＜0.001). The world-standard incidence and mortality of lung cancer, esophageal cancer, gastric cancer, liver cancer and colorectal cancer decreased from 2011 to 2020. The AAPCs of the world-standard incidence were -4.0%, -12.3%, -9.4%, -6.0% and -1.6%, respectively. The AAPCs of the world-standard mortality were -4.9%, -11.3%, -8.5%, -5.7% and -3.3%, which were statistically significant. The incidence of thyroid cancer increased rapidly, the AAPC of which was 9.7% (＜0.001). The rates of female breast cancer and male prostate cancer in Hebei Province were stable. The world-standard incidence and mortality of cancer in Hebei Provincial cancer registries areas show a downward trend from 2011 to 2020. However, the cancer incidence and mortality in Hebei Province are still at high levels. It's necessary to strengthen cancer prevention and control in Hebei Province, improve the awareness of cancer prevention and control in the whole society, and promote the concept of tertiary cancer prevention to reduce the cancer burden in Hebei Province.
了解近年来河北省癌症疾病负担，并分析2011年至2020年河北省癌症的变化趋势。收集了2011 - 2020年期间河北省38个癌症登记处的癌症发病和死亡数据。分别计算了各地区、性别和年龄的发病率（死亡率）、标准化发病率（死亡率）和构成比，并总结了我省主要癌症的发病和死亡情况。分别采用2000年中国标准人口构成和Segi世界人口构成计算中国和世界人口的年龄标准化发病率（死亡率）。对发病率和死亡率进行趋势分析，并计算平均年度百分比变化（AAPC）。2020年，中国癌症粗发病率和年龄标准化发病率分别为229.36/10万和147.06/10万。该省报告的新发病例估计有171600例。中国癌症粗死亡率和年龄标准化死亡率分别为146.38/10万和85.33/10万。该省的死亡估计人数为108900人。在河北省癌症登记地区，84%的癌症患者年龄在50岁及以上。2011年至2020年，河北省癌症的发病率和死亡率呈下降趋势。AAPC为-4.2%（＜0.001），从2011年的206.61/10万降至2020年的143.74/10万。2011年癌症世界标准死亡率为147.69/10万，2020年降至84.79/10万。AAPC为-5.7%（＜0.001）。2011年至2020年，肺癌、食管癌、胃癌、肝癌和结直肠癌的世界标准发病率和死亡率下降。世界标准发病率的AAPC分别为-4.0%、-12.3%、-9.4%、-6.0%和-1.6%。世界标准死亡率对应的AAPC分别为-4.9%、-11.3%、-8.5%、-5.7%和-3.3%，差异有统计学意义。甲状腺癌发病率迅速上升，AAPC为9.7%（＜0.001）。河北省女性乳腺癌和男性前列腺癌发病率稳定。2011年至2020年，河北省癌症登记地区癌症的世界标准发病率和死亡率呈下降趋势。然而，河北省癌症的发病率和死亡率仍处于较高水平。有必要加强河北省癌症防控工作，提高全社会癌症防控意识，推广癌症三级预防理念，以减轻河北省的癌症负担。
