Kritya Mangesh, Shamim Shariq, Sharma Vaibhav, Sahai Akshat, Thayumanavan Thirugnanasambandam, Arain Salman A
Department of Structural Heart, Houston Methodist Research Institute, Houston, Texas, USA.
Department of Cardiovascular Disease, St. Louis Heart and Vascular, St. Louis, Missouri, USA.
Catheter Cardiovasc Interv. 2025 Jul;106(1):288-293. doi: 10.1002/ccd.31552. Epub 2025 Apr 23.
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) is technically more challenging than non-CTO PCI. The development of novel CTO-specific PCI techniques, such as hydrodynamic contrast recanalization (HDR), has led to improved technical success with low complication rates. We present a case of successful single-session PCI of multiple CTOs using HDR in an elderly patient. Our report highlights the feasibility and advantages of single-session complete revascularization in patients with multiple CTOs.
A 71-year-old woman with multiple comorbidities, including CAD, heart failure with reduced ejection fraction (HFrEF), chronic kidney disease stage 3 (CKD), and lung cancer in remission, was admitted with NYHA class IV symptoms. Coronary angiography revealed CTO of all three major coronary arteries. Given her high surgical risk and frailty, percutaneous revascularization was recommended by the Heart Team. The patient underwent successful HDR-facilitated CTO PCI of the left anterior descending (LAD), left circumflex (LCX), and right coronary arteries (RCA) in a single session. TIMI 3 flow was restored in all three vessels after successful drug-eluting stent (DES) placement. The patient's symptoms markedly improved postprocedure.
HDR is a novel CTO crossing technique that uses contrast modulation beyond the boundary of the proximal cap to facilitate the passage of polymer-jacketed wires. Reported advantages of HDR include a faster crossing time and side branch preservation. Using HDR, we recanalized multiple CTOs in an elderly patient in under 3 h, achieving single-session complete revascularization that improved clinical outcomes and minimized repeat procedural risks. This case highlights the potential role of HDR as a safe and efficient adjunct to conventional CTO PCI techniques in achieving optimal outcomes.
慢性完全闭塞病变(CTO)的经皮冠状动脉介入治疗(PCI)在技术上比非CTO的PCI更具挑战性。新型CTO特异性PCI技术的发展,如流体动力造影再通术(HDR),已使技术成功率提高且并发症发生率降低。我们报告了一例老年患者使用HDR成功单次完成多支CTO病变PCI的病例。我们的报告强调了多支CTO病变患者单次完全血运重建的可行性和优势。
一名71岁女性,合并多种疾病,包括冠心病、射血分数降低的心力衰竭(HFrEF)、慢性肾脏病3期(CKD)和缓解期肺癌,因纽约心脏协会(NYHA)IV级症状入院。冠状动脉造影显示三支主要冠状动脉均为CTO病变。鉴于其手术风险高且身体虚弱,心脏团队建议进行经皮血运重建。患者在单次手术中成功接受了HDR辅助的左前降支(LAD)、左旋支(LCX)和右冠状动脉(RCA)CTO PCI。成功植入药物洗脱支架(DES)后,三支血管均恢复了TIMI 3级血流。术后患者症状明显改善。
HDR是一种新型的CTO病变通过技术,它利用近端帽边界以外的造影剂调制来促进聚合物包裹导丝的通过。HDR的报告优势包括更快的通过时间和侧支保留。使用HDR,我们在不到3小时内使一名老年患者的多支CTO病变再通,实现了单次完全血运重建,改善了临床结局并将再次手术风险降至最低。该病例突出了HDR作为传统CTO PCI技术安全有效的辅助手段在实现最佳结局方面的潜在作用。