Zou Hua, Zhang Meibian, Xue Panqi, Wei Fang, Li Fei, Fang Xinglin, Lou Xiaoming, Zhou Lifang
Institute of Occupational Health and Radiation Protection, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Front Public Health. 2025 Apr 9;13:1542879. doi: 10.3389/fpubh.2025.1542879. eCollection 2025.
We report a rare incident of acute arsine poisoning when cleaning an industrial purifier to enhance awareness for the prevention of arsine poisoning incidents in the family-run workshop. In this incident, three workers of a family-run cleaning workshop developed symptoms of headache, abdominal pain, chills, fatigue, and hematuria after cleaning an industrial purifier, with a latency period 4-6 h after exposure. Field investigations and laboratory tests were used to investigate the poisoning incident. Red blood cell counts and levels of hemoglobin, alanine transaminase, and urinary arsenic (As) increased, and urinary protein and occult blood tests indicated strongly positive results. The cleaning workshop undertook no effective measures to prevent occupational poisoning. The As concentration in flame retardants, dust on the surface of the industrial purifier, and water in the soaking pool was 269 mg/kg, 1.72 × 10 mg/kg, and 6.89 × 10 mg/L, respectively. This incident highlighted the association of the acute arsine poisoning during the cleaning of an industrial purifier with poor occupational health management practices. Effective measures for the prevention of the acute poisoning should therefore be undertaken.
我们报告了一起罕见的急性砷化氢中毒事件,该事件发生在清理工业净化器时,目的是提高对家庭作坊中砷化氢中毒事件预防的认识。在这起事件中,一家家庭清洁作坊的三名工人在清理工业净化器后出现头痛、腹痛、寒战、疲劳和血尿症状,接触后潜伏期为4 - 6小时。通过现场调查和实验室检测对中毒事件进行了调查。红细胞计数、血红蛋白、丙氨酸转氨酶水平以及尿砷(As)升高,尿蛋白和潜血试验呈强阳性结果。该清洁作坊未采取有效的职业中毒预防措施。阻燃剂中的砷浓度、工业净化器表面灰尘中的砷浓度以及浸泡池水中的砷浓度分别为269mg/kg、1.72×10mg/kg和6.89×10mg/L。这起事件凸显了工业净化器清理过程中急性砷化氢中毒与不良职业健康管理做法之间的关联。因此,应采取有效的预防急性中毒措施。