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病例报告:一名患有难治性系统性肥大细胞增多症合并AML1::ETO+急性髓系白血病的儿科患者对吉妥珠单抗-奥佐米星迅速产生反应。

Case Report: Rapid response to gemtuzumab-ozogamicin in a pediatric patient with refractory systemic mastocytosis with AML1::ETO+ acute myeloid leukemia.

作者信息

Xue Song, Chen Man, Sun Hui-Peng, Wang Tong, Zhang Li-Na, Cao Xing-Yu

机构信息

Department of Bone Marrow Transplant, Beijing Lu Daopei Hospital, Beijing, China.

Division of Pathology & Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, China.

出版信息

Front Immunol. 2025 Apr 9;16:1566805. doi: 10.3389/fimmu.2025.1566805. eCollection 2025.

Abstract

This article describes a 6-year-old patient diagnosed with "systemic mastocytosis with AML1::ETO+ AML", he experience refractory disease during the course of treatment and salvage treatment was ineffective. The patient was administered gemtuzumab-ozogamicin therapy, resulting in rapid remission.

摘要

本文描述了一名6岁患者,被诊断为“伴有AML1::ETO+急性髓系白血病的系统性肥大细胞增多症”,他在治疗过程中出现难治性疾病,挽救治疗无效。该患者接受了吉妥珠单抗-奥唑米星治疗,迅速获得缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff25/12014624/4d5b3a695415/fimmu-16-1566805-g001.jpg

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