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年轻成年人中的缺铁性贫血与缺血性中风

Iron Deficiency Anemia and Ischemic Stroke in Young Adults.

作者信息

Gollamudi Jahnavi, Al-Kindi Sadeer, Nayak Lalitha

机构信息

Section of Hematology-Oncology Department of Internal Medicine University of Cincinnati Cincinnati Ohio USA.

Department of Cardiology DeBakey Heart and Vascular Center Houston Methodist Hospital Houston Texas USA.

出版信息

EJHaem. 2025 Apr 23;6(2):e70008. doi: 10.1002/jha2.70008. eCollection 2025 Apr.

Abstract

BACKGROUND

Iron deficiency anemia (IDA) is the most common cause of anemia and is linked to higher arterial stroke risk in children, but its effect in adults remains unclear.

METHODS

We performed a retrospective study examining the prevalence of IDA in young adults with and without ischemic stroke.

RESULTS

We found that the prevalence of IDA was five times higher in patients with ischemic stroke than those without stroke (5% vs. 1.05%).

CONCLUSION

IDA independently increased the odds of an ischemic stroke by 39% ( < 0.001). Given the global burden of IDA, effective screening strategies are necessary.

摘要

背景

缺铁性贫血(IDA)是贫血最常见的病因,与儿童动脉性卒中风险增加有关,但其在成人中的影响尚不清楚。

方法

我们进行了一项回顾性研究,调查有无缺血性卒中的年轻成人中IDA的患病率。

结果

我们发现,缺血性卒中患者的IDA患病率比无卒中患者高五倍(5%对1.05%)。

结论

IDA使缺血性卒中的几率独立增加了39%(P<0.001)。鉴于IDA的全球负担,有效的筛查策略是必要的。

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本文引用的文献

1
Iron deficiency anemia among women: An issue of health equity.
Blood Rev. 2024 Mar;64:101159. doi: 10.1016/j.blre.2023.101159. Epub 2023 Nov 29.
2
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Am J Hematol. 2023 Oct;98(10):1532-1539. doi: 10.1002/ajh.27021. Epub 2023 Jul 12.
3
Downregulated KLF2 in polycythemia vera and essential thrombocythemia induces prothrombotic gene expression.
Blood Adv. 2023 Mar 14;7(5):712-717. doi: 10.1182/bloodadvances.2022008052.
4
Characterization of the rate, predictors, and thrombotic complications of thrombocytosis in iron deficiency anemia.
Am J Hematol. 2020 Oct;95(10):1180-1186. doi: 10.1002/ajh.25925. Epub 2020 Aug 4.
6
Iron-Deficiency and Estrogen Are Associated With Ischemic Stroke by Up-Regulating Transferrin to Induce Hypercoagulability.
Circ Res. 2020 Aug 14;127(5):651-663. doi: 10.1161/CIRCRESAHA.119.316453. Epub 2020 May 26.
7
Iron deficiency-induced thrombocytosis increases thrombotic tendency in rats.
Haematologica. 2021 Mar 1;106(3):782-794. doi: 10.3324/haematol.2019.245092.
9
The Global Burden of Anemia.
Hematol Oncol Clin North Am. 2016 Apr;30(2):247-308. doi: 10.1016/j.hoc.2015.11.002.
10
Association between ischemic stroke and iron-deficiency anemia: a population-based study.
PLoS One. 2013 Dec 9;8(12):e82952. doi: 10.1371/journal.pone.0082952. eCollection 2013.

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