Leschot N J, Verjaal M, Treffers P E
Br J Obstet Gynaecol. 1985 Aug;92(8):804-7. doi: 10.1111/j.1471-0528.1985.tb03049.x.
The obstetric outcome of 3000 pregnancies with midtrimester amniocentesis was followed in all but one patient. Thirty pregnancies ended in fetal death or abortion within 3 weeks after amniocentesis. Chronologically 23 of these occurred in the first series of 1500 pregnancies and the remaining seven fetal deaths/abortions within 3 weeks after amniocentesis occurred in the second series of 1500 pregnancies. Fetal loss within 3 weeks after amniocentesis was apparently related to the experience of the obstetrician and to the use of modern ultrasound guidance. It is concluded that the risk of fetal death after midtrimester amniocentesis is approximately 0.5%, if only experienced obstetricians using modern techniques are involved.
除一名患者外，对3000例孕中期羊膜腔穿刺术的妊娠结局进行了随访。30例妊娠在羊膜腔穿刺术后3周内以胎儿死亡或流产告终。按时间顺序，其中23例发生在首批1500例妊娠中，其余7例羊膜腔穿刺术后3周内的胎儿死亡/流产发生在第二批1500例妊娠中。羊膜腔穿刺术后3周内的胎儿丢失显然与产科医生的经验以及现代超声引导的使用有关。得出的结论是，如果仅由经验丰富的产科医生使用现代技术，孕中期羊膜腔穿刺术后胎儿死亡的风险约为0.5%。
