Starost Matthew F
Office of Research Services, Division of Veterinary Resources, National Institutes of Health, Bethesda, Maryland, USA.
Vet Med Sci. 2025 May;11(3):e70378. doi: 10.1002/vms3.70378.
Primary mesenchymal tumours of the spleen in non-human primates are exceedingly rare. We report on a 13-year-old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma with widespread metastasis. This is the first report of a splenic leiomyosarcoma in a non-human primate.
非人灵长类动物脾脏的原发性间充质肿瘤极为罕见。我们报告了一只13岁的雌性恒河猴,它出现肝脏、脾脏肿大以及肺部多发肿块。宏观、微观及免疫组化检查显示为脾平滑肌肉瘤伴广泛转移。这是非人灵长类动物脾平滑肌肉瘤的首例报告。