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一只恒河猴(猕猴)发生的伴有转移的原发性脾平滑肌肉瘤

Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta).

作者信息

Starost Matthew F

机构信息

Office of Research Services, Division of Veterinary Resources, National Institutes of Health, Bethesda, Maryland, USA.

出版信息

Vet Med Sci. 2025 May;11(3):e70378. doi: 10.1002/vms3.70378.

Abstract

Primary mesenchymal tumours of the spleen in non-human primates are exceedingly rare. We report on a 13-year-old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma with widespread metastasis. This is the first report of a splenic leiomyosarcoma in a non-human primate.

摘要

非人灵长类动物脾脏的原发性间充质肿瘤极为罕见。我们报告了一只13岁的雌性恒河猴,它出现肝脏、脾脏肿大以及肺部多发肿块。宏观、微观及免疫组化检查显示为脾平滑肌肉瘤伴广泛转移。这是非人灵长类动物脾平滑肌肉瘤的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0feb/12020913/c26734ee7ae5/VMS3-11-e70378-g003.jpg

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