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利用美国外科医师学会国家外科质量改进计划(ACS-NSQIP)评估结肠切除术后再入院情况及早期出院的应用:现在是广泛应用的时候了吗?

Readmission and Adoption of Early Discharge After Colectomy Using ACS-NSQIP: Is It Time for Widespread Adoption?

作者信息

Gaetani Racquel S, Jonczyk Michael M, Kleiman David A, Kuhnen Angela H, Marcello Peter W, Saraidaridis Julia T, Abelson Jonathan S

机构信息

Department of Colon and Rectal Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts.

Department of Colon and Rectal Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts.

出版信息

J Surg Res. 2025 May;309:242-248. doi: 10.1016/j.jss.2025.03.021. Epub 2025 Apr 23.

Abstract

INTRODUCTION

The timing of post-operative discharge following colectomy procedures remains a subject of debate among colorectal surgeons. Prior studies have demonstrated the safety and adoption of early discharge within 24 h after elective colectomy in carefully selected patients.

METHODS

This retrospective cohort study utilizing data from the American COllege of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) from 2012 to 2021. Adult patients undergoing elective partial colectomy with primary anastomosis and documented length of stay were included. Patients were stratified into early (< 24) and non early (≥24 h) discharge groups. Propensity score matching was used to control for baseline demographics and non-modifiable risk factors. Primary outcomes included 30-day readmission rates and adoption trends of early discharge over time.

RESULTS

A total of 282,037 patients met inclusion criteria of which 6364 (2.3%) were discharged within 24 h. On propensity score matching the early discharge cohort had a statistically significantly lower rate of readmission (5.5% versus 7.3%, P < 0.001). Additionally, the early discharge group had a significantly reduced rate of anastomotic leak (1.0 versus 2.6%), ileus (2.0% versus 7.6%), and rate of reoperation (1.2% versus 4.0%) (P < 0.001). The proportion of early discharge colectomies increased from 0.8% in 2012 to 3.6% in 2021 (P < 0.001).

CONCLUSIONS

In carefully selected patients, early discharge after colectomy with primary anastomosis does not increase the risk of readmission, reoperation, or 30-d complication rates. Furthermore, the increasing trend in utilization of early discharge after colectomy suggests an increasing acceptance of this practice, though it remains a minority of all colectomies performed among institutions participating in ACS-NSQIP.

摘要

引言

结肠切除术后出院时间在结直肠外科医生中仍是一个有争议的话题。先前的研究已证明,在经过精心挑选的患者中,择期结肠切除术后24小时内提前出院是安全可行的。

方法

本回顾性队列研究使用了美国外科医师学会国家外科质量改进计划(ACS-NSQIP)2012年至2021年的数据。纳入接受择期部分结肠切除并进行一期吻合且有住院时长记录的成年患者。患者被分为提前(<24小时)出院组和非提前(≥24小时)出院组。倾向评分匹配用于控制基线人口统计学和不可改变的风险因素。主要结局包括30天再入院率以及提前出院随时间的采用趋势。

结果

共有282,037名患者符合纳入标准,其中6364名(2.3%)在24小时内出院。倾向评分匹配后,提前出院队列的再入院率在统计学上显著更低(5.5%对7.3%,P<0.001)。此外,提前出院组吻合口漏发生率(1.0%对2.6%)、肠梗阻发生率(2.0%对7.6%)和再次手术率(1.2%对4.0%)均显著降低(P<0.001)。结肠切除术后提前出院的比例从2012年的0.8%增至2021年的3.6%(P<0.001)。

结论

在精心挑选的患者中,一期吻合的结肠切除术后提前出院不会增加再入院、再次手术风险或30天并发症发生率。此外,结肠切除术后提前出院的使用呈上升趋势,这表明这种做法越来越被接受,尽管在参与ACS-NSQIP的机构所进行的所有结肠切除术中,它仍占少数。

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