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针对外翻性骨关节炎的定制型全膝关节置换术导致在低限制植入物中使用最薄厚度的聚乙烯衬垫。

Patient-Specific total knee arthroplasty for valgus osteoarthritis results in the use of minimal thickness polyethylene liners in low constraint implants.

作者信息

Pagani Nicholas, Mazzocco John, Thienpont Emmanuel, Smith Eric

机构信息

New England Baptist Hospital, Boston, USA.

Tufts Medical Center, Boston, USA.

出版信息

Arch Orthop Trauma Surg. 2025 Apr 24;145(1):263. doi: 10.1007/s00402-025-05873-1.

Abstract

BACKGROUND

Correction of valgus knee deformity during total knee arthroplasty (TKA) can present numerous challenges. This study assessed the ability of a patient-specific knee design to allow easier intraoperative balancing of valgus knees in primary TKA.

MATERIALS AND METHODS

This study utilized a database consisting of de-identified computed tomography (CT) scans, low constraint knee designs (CR or PS), tibial and femoral implant dimensions, and implanted polyethylene (PE) thickness for all patients who underwent primary TKA with a patient-specific knee design provided by Conformis Inc. (Boston, MA, US). Data were analyzed for knee design, coronal deformity, native posterior and distal femoral offset, and PE thickness.

RESULTS

A total of 26,227 cases were included, of which 25% had valgus deformity. In the PS group, the thinnest available PE (6 mm) was used for 64% of varus cases and 68% of valgus cases (P = 0.004). There was no difference in the distribution of thin (≤ 8 mm) and thick (> 8 mm) PE between varus or valgus knees with 0-5 degrees or > 10 degrees of deformity. Knees with varus deformity of 5-10 degrees were more likely to receive a thick PE than knees with valgus deformity of 5-10 degrees. For the CR group, the thinnest available PE (6 mm) was used in 77% of varus cases and 76% of valgus cases (P = 0.12). There was no difference in the distribution of thin and thick PE between varus or valgus knees regardless of deformity. Over 99% of CR knees received PE with thicknesses 8 mm or less, regardless of degree of preoperative varus or valgus deformity.

CONCLUSIONS

These results indicate that patient-specific instrumentation in TKA can facilitate valgus deformity correction without requiring increased PE thickness to achieve balancing. Patient-specific knee designs may reduce the difficulty of valgus knee correction while allowing the use of minimal thickness PEs in low constraint TKA implants.

摘要

背景

全膝关节置换术(TKA)中纠正膝外翻畸形可能会带来诸多挑战。本研究评估了一种定制膝关节设计在初次TKA中使膝外翻更容易实现术中平衡的能力。

材料与方法

本研究利用了一个数据库,该数据库包含所有接受由Conformis公司(美国马萨诸塞州波士顿)提供的定制膝关节设计的初次TKA患者的去识别化计算机断层扫描(CT)图像、低约束膝关节设计(CR或PS)、胫骨和股骨植入物尺寸以及植入的聚乙烯(PE)厚度。对膝关节设计、冠状面畸形、股骨近端和远端的自然偏移以及PE厚度进行了数据分析。

结果

共纳入26227例病例,其中25%存在外翻畸形。在PS组中,最薄的可用PE(6mm)用于64%的内翻病例和68%的外翻病例(P = 0.004)。畸形0 - 5度或>10度的内翻或外翻膝关节之间,薄(≤8mm)和厚(>8mm)PE的分布没有差异。5 - 10度内翻畸形的膝关节比5 - 10度外翻畸形的膝关节更有可能接受厚PE。对于CR组,最薄的可用PE(6mm)用于77%的内翻病例和76%的外翻病例(P = 0.12)。无论畸形程度如何,内翻或外翻膝关节之间薄PE和厚PE的分布没有差异。超过99%的CR膝关节接受的PE厚度为8mm或更小,无论术前内翻或外翻畸形程度如何。

结论

这些结果表明,TKA中的定制器械可以促进膝外翻畸形的纠正,而无需增加PE厚度来实现平衡。定制膝关节设计可能会降低膝外翻矫正的难度,同时允许在低约束TKA植入物中使用最小厚度的PE。

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