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在后稳定型和限制性髁型膝关节置换术中,聚乙烯损伤随内翻植入物对线增加。

Polyethylene Damage Increases With Varus Implant Alignment in Posterior-stabilized and Constrained Condylar Knee Arthroplasty.

作者信息

Li Zhichang, Esposito Christina I, Koch Chelsea N, Lee Yuo-Yu, Padgett Douglas E, Wright Timothy M

机构信息

Department of Biomechanics, Hospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.

Arthritis Clinic and Research Center, Peking University People's Hospital, Beijing, China.

出版信息

Clin Orthop Relat Res. 2017 Dec;475(12):2981-2991. doi: 10.1007/s11999-017-5477-4. Epub 2017 Aug 18.

Abstract

BACKGROUND

Implant malalignment in primary TKA has been reported to increase stresses placed on the bearing surfaces of implant components. We used a longitudinally maintained registry coupled with an implant retrieval program to consider whether preoperative, postoperative, or prerevision malalignment was associated with increased risk of revision surgery after TKA.

QUESTIONS/PURPOSES: (1) What is the relative polyethylene damage on medial and lateral compartments of the tibial plateaus from revised TKAs? (2) Does coronal TKA alignment affect implant performance, such that TKAs aligned in varus are predisposed to experience increased polyethylene damage? (3) Does TKA alignment differ between postoperative and prerevision radiographs, and if so, what does this difference suggest about the mechanical contact load placed on a knee with a TKA?

METHODS

Between 2007 and 2012, we performed 18,065 primary TKAs at our institution. By March 2016, 178 of those TKAs (1%) were revised at our center at least 2 years after primary surgery at our institution. Eighteen of those TKAs were excluded from this analysis because the tibial insert was not explanted during revision surgery, and four more were excluded because the inserts were lost or returned to the patient before the study was initiated, leaving 156 retrieved polyethylene tibial inserts (in 153 patients) revised at greater than 2 years after the primary TKA for this retrospective study. Patients who underwent revision surgery elsewhere were not considered here, since this study depended on having retrieved components. Polyethylene damage modes of burnishing, pitting, scratching, delamination, surface deformation, abrasion, and third-body debris were subjectively graded on a scale of 0 to 3 to reflect the extent and severity of each damage mode. On preoperative, postoperative, and prerevision radiographs, overall alignment, femoral alignment, and tibial alignment in the coronal plane were measured according to the protocol recommended by the Knee Society.

RESULTS

Knees with more overall varus alignment after TKA had increased total damage on the retrieved tibial inserts (Spearman's rank correlation coefficients of -0.3 [95% CI, -0.4 to -0.1; p = 0.001]). We also found revised TKAs tended to drift back into greater varus before revision surgery, with a mean (SD) of 3.6° ± 4.0° valgus for postoperative alignment compared with 1.7° ± 6.4° prerevision (p = 0.04).

CONCLUSIONS

Despite surgical efforts to achieve neutral mechanical alignment, remaining varus alignment places an increased contact load on the polyethylene articular surfaces. The drift toward further varus alignment postoperatively is consistent with the knee adduction moment remaining high after surgery.

CLINICAL RELEVANCE

While we found a predisposition toward recurrence of the preoperative varus deformity, we did not find increased medial as opposed to lateral polyethylene damage, which may be explained by the curve-on-curve toroidal design of the articulating surfaces of the TKA implants in this study.

摘要

背景

据报道,初次全膝关节置换术(TKA)中植入物排列不齐会增加植入物部件承重表面的应力。我们采用纵向维护的登记系统并结合植入物取出计划,来探讨术前、术后或翻修前的排列不齐是否与TKA术后翻修手术风险增加相关。

问题/目的:(1)翻修TKA术后,胫骨平台内侧和外侧间室的聚乙烯相对损伤情况如何?(2)冠状面TKA排列是否会影响植入物性能,使得内翻排列的TKA更容易出现聚乙烯损伤增加?(3)术后与翻修前X线片上的TKA排列是否不同,如果不同,这种差异对于TKA膝关节上的机械接触负荷意味着什么?

方法

2007年至2012年期间,我们在本机构进行了18065例初次TKA。截至2016年3月,其中178例(1%)在本机构初次手术后至少2年在我们中心进行了翻修。其中18例TKA被排除在本分析之外,原因是翻修手术期间未取出胫骨衬垫,另有4例被排除,原因是在研究开始前衬垫丢失或返还给了患者,本回顾性研究最终纳入156例(153例患者)初次TKA术后超过2年翻修时取出的聚乙烯胫骨衬垫。在其他地方接受翻修手术的患者未纳入本研究,因为本研究依赖于取出的部件。聚乙烯的磨损、点蚀、划痕、分层、表面变形、擦伤和第三体碎片等损伤模式主观分级为0至3级,以反映每种损伤模式的程度和严重程度。根据膝关节协会推荐的方案,在术前、术后和翻修前X线片上测量冠状面的整体排列、股骨排列和胫骨排列。

结果

TKA术后整体内翻排列更多的膝关节,取出的胫骨衬垫总损伤增加(斯皮尔曼等级相关系数为-0.3 [95% CI,-0.4至-0.1;p = 0.001])。我们还发现,翻修TKA在翻修手术前往往会向内翻进一步偏移,术后排列的平均(标准差)外翻角度为3.6°±4.0°,而翻修前为1.7°±6.4°(p = 0.04)。

结论

尽管手术努力实现中立的机械排列,但残留的内翻排列会增加聚乙烯关节表面的接触负荷。术后向内翻排列进一步偏移与术后膝关节内收力矩仍然较高一致。

临床意义

虽然我们发现术前内翻畸形有复发倾向,但未发现内侧聚乙烯损伤相对于外侧增加,这可能由本研究中TKA植入物关节表面的曲线对曲线环形设计来解释。

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